Gordon's Notes

Researchers are taking seriously the use of hydroxychloroquine for COVID-19 therapy : Both chloroquine and hydroxychloroquine inhibit SARS-...

My right wrist hurt the other day. A sudden sharp annoying pain. Maybe a tendon, maybe my arthritis acting up. So I did my usual amateur se...

A footnote in my post on Kateva’s liver disease  linked to a NYT article on  CHIP (clonal hematopoiesis of indeterminate potential) . Wikipe...

My familial arthritis showed up in one finger a few years ago, but in December of 2015 it became a bigger deal [1]. It looked like an early...

While doing some research on interstitial cystitis  Google uncovered an extraordinary claim by the Cleveland Clinic’s Raymond Rackley : M...

Wikipedia has the party line description of these buggers. Emphases mine. Heberden's node Heberden’s nodes are hard or bony swellings...

For personal reasons I’ve been doing a deep dive into current medical knowledge of osteoarthritis — particularly the relatively early and ag...

See also:  Arthritis - the feeds and queries (reference post) . There’s something problematic about human tendons and cartilage. A wide ran...

I feel like I’m tied to a railroad track, and see the light of the train approaching. And I don’t know if it’s one mile away, or 500.   Anon...

The extremophiles  are at home in near boiling water and the deep crust of the earth. Every ecological niche is colonized by life; and life ...

The immune system is an impossible, incomprehensible, machine. It is not even a ’system’ — evolution is not so modular. We name it as a thin...

This mornings board review included looking at the evolution of “inflammatory osteoarthritis” from 1970 to 2015. What was once described as...

In the spirit of my medical anecdotes , I present my left wrist. Late Monday afternoon, while typing, I developed sharp pains in my left...

One of the interesting things about being old (45+, sorry to tell you that) and active and is that we develop conditions that we then get to...

After decades of blood donation I was rejected in 2010 because of a false positive HTLV I/II test. I was annoyed, but not too concerned. I...

From 1910 to 1984 medical progress was extremely swift. After 1984, not so much. As I wrote in 1998 ... Gordon's Notes: Challenges to...

The goal of modern medicine is not to extend life. It is to extend wellness. Sirtuin activators, enhanced versions of Resveratrol , can do...

By an odd bit of synchronicity I'm simultaneously engaged with leading edge research in " Translational Bioinformatics " and r...

Nor your father's definition of the human. In the past few weeks we've read of toxic viral payloads in sometimes commensal bacteria ...