Gordon's Notes

Gabapentin  was developed as a focal seizure medication and has been found to be effective for neuropathic pain syndromes in diabetic neurop...

It's Nov 6, 2020 and I believe Trump's presidency is ending. I look forward to forgetting him, but one day I'll be asked what al...

I remember COVID-03 (Coronavirus disease 2003, known then as SARS) caused by Novel Coronavirus 1 (SARS-CoV-1). It was frightening and puzzli...

Originally published in the NYT Oct 28, 1956 by Waldemar Kaempffert . Reprinted as Climate Science in 1956 and 2015 | HuffPost : The gener...

First came CHIP - Clonal hematopoiesis of indeterminate potential  (Jan 2018) … a bizarre accumulation of mutated stem cells in bone marro...

I’ve been a fan of the National Library of Medicine’s medical literature service through MEDLARS to MEDLINE to Grateful Med (my fave) to the...

In the real world HRC is President and the GOP is beginning a painful reform process that will lead to a far better conservative party and a...

From  Backreaction: Dear Dr B: If photons have a mass, would this mean special relativity is no longer valid?  I learn that while Einstein m...

Phenazopyridine is an old drug, discovered in the 1930s. Chemically it’s classified as an “ azo dye ”, these chemicals are usually used to ...

I think of  In the Pipeline ’s  Derek Lowe  as a small ‘m’ marketarian. He has more confidence in the “invisible hand” of markets than I, bu...

While doing some research on interstitial cystitis  Google uncovered an extraordinary claim by the Cleveland Clinic’s Raymond Rackley : M...

My mother had a bottle of thalidomide on the shelf. It was her first pregnancy and she was sick. Thalidomide was the hot new treatment for...

See also:  Arthritis - the feeds and queries (reference post) . There’s something problematic about human tendons and cartilage. A wide ran...

I feel like I’m tied to a railroad track, and see the light of the train approaching. And I don’t know if it’s one mile away, or 500.   Anon...

The extremophiles  are at home in near boiling water and the deep crust of the earth. Every ecological niche is colonized by life; and life ...

Between 2007 and 2008 my work life got unusually exciting. Most of the time I work on software development in well understood aspects of med...

My son is starting to do … physics. It is fair to say I am more excited about this than he is. There is a reason I have a copy of the 1973 ...

Like most people, my neurons were rebooted a few times between birth and adulthood . So I don’t remember that much about childhood, but I do...

Over the past two decades it has become apparent that the knowledge base for clinical medicine has been corrupted by publication bias, posit...

My 16yo is having his wisdom teeth removed tomorrow. Blame it on human domestication. The Economist explains the process . Domestication, w...