Sugar in space provides clue to origin of life

Spaceflight Now | Breaking News | Sugar in space provides clue to origin of life

Although the chemistry on Earth and in interstellar clouds is much different, the results can be very similar. This and other recent studies show that prebiotic chemistry -- the formation of the molecular building blocks necessary for the creation of life -- occurs in interstellar clouds long before that cloud collapses to form a new solar system with planets. 'Many of the interstellar molecules discovered to date are the same kinds detected in laboratory experiments specifically designed to synthesize prebiotic molecules. This fact suggests a universal prebiotic chemistry,' said Jan M. Hollis of NASA's Goddard Space Flight Center in Greenbelt, MD. This suggests that the molecular building blocks for the creation of life on a new planet might get a head start in the dust of interstellar clouds.

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The galaxy is a petri dish for life carrying planets. Very strange.

Asking the big questions: Are we alone? What happens to civilizations like our's?

The New York Times Magazine - CHARLES SIEBERT - The Genesis Project

To put it mildly, this is an interest of mine. The most recent discoveries in extrasolar planetary science favor an abundance of earthlike planets (Bayesian reasoning -- they've chopped off the rare-planet end of the probability curve). This biases the hoary Drake Equation towards the likelihood of life, even technological life.

The Genesis Project (love the name the NYT title hack gave it) is about filling out other terms in the Drake Equation. It points in some weird directions. Francis Crick gained a reputation as a fallen genius because of his support for the hypothesis that life on earth arose by deliberate "seeding" of a newly formed planet. The idea was not knew to Crick, cometary seeding of life has been popular in science fiction for generations.

Yet Fermi's Paradox remains -- we don't find godlike aliens underfoot. Which leads to the most interesting question of all -- what happens to technocentric civilizations?

September 26, 2004

...The Stardust mission, however, is typical of a number of projects to divine life's origins, all part of a $75-million-a-year scientific enterprise now being financed by NASA. It is known as astrobiology.

The appellation invokes images of ferns in outer space, or interstellar swamps, but these are mundane imaginings compared with the various avenues of exploration being pursued by astrobiologists. There are projects like drilling into the earth's boiling-hot deep-sea vents or icy dark Antarctic waters in order to do DNA analysis of primitive life forms. Or trying to replicate in the laboratory the moment when the chemical earth first transformed into a biological one. Or lassoing a multibillion-year-old comet in search of organic compounds like amino acids and carbon, the so-called building blocks of life.

... There was a time -- right up until the early 1950's, in fact -- when the sorts of questions now being addressed by astrobiology were the stuff of either myth and science fiction, or of only the most marginal, far-fetched or pie-in-the-sky kinds of science. Now, however, we face a strangely reverse reality: the state of our knowledge has evolved to the point where our previous conjecturing about life's origin has been exposed as woefully myopic and parochial, not nearly far-fetched or skyward-looking enough.

... It is a quest that is being pursued from three directions: comparative analysis of DNA on earth; biochemical synthesis of life in the lab, or ''test-tube evolution''; and, finally, examination of the various organic compounds that exist in the depths of outer space -- perhaps the ideal laboratory, because of both its deep history and inherent lack of contamination.

Of astrobiology's three approaches, the first, DNA analysis, is perhaps the most traditional mode of inquiry, or at least the most grounded. Precisely because all life forms are made of the same stuff, are all so-called ''DNA-protein-based organisms,'' scientists can now use comparative DNA analysis to trace the common roots of life's collective family tree further back than ever imagined.

... There is, for example, a consensus now about the existence and the essential character of life's common ancestor, the great, great, great (to the power of a gazillion) grandparent of you and me and everything else that we see (or can't see) living around us. It even has a name: LUCA, or Last Universal Common Ancestor, although some prefer the name Cenancestor, from the Greek root ''cen'' (meaning ''together'') and others favor LCA, or Last Common Ancestor.

There is very little known about LUCA, though scientists currently agree on two things. One, that it had to have existed. And two, that it had to have been extremely rugged. As recently as the mid-70's there were thought to be only two domains of life on earth: the prokaryotes -- small, single-celled bacteria lacking a nucleus or other complex cellular structures; and the eukaryotes -- organisms made of one or more cells with a nucleus, a category embracing everything from complex multicellular entities, like mammals, reptiles, birds and plants, to the single-celled amoeba.

In 1977, however, a molecular biologist from the University of Illinois named Carl Woese identified within the prokaryotes a genetically distinct class of bacteria now known as the archaea, many of them primitive, single-celled organisms known as ''extremophiles'' because they live in extreme environments like volcanic vents or Antarctic waters. When the DNA of archaea was compared with that of prokaryotes and eukaryotes, it became clear that the trifurcation of life from LUCA occurred far earlier than previously believed, well over three billion years ago, when there was little or no oxygen in the earth's atmosphere.

[jf: In other words the extremophile discoveries were (perhaps literally?) earthshattering. They radically changed our thoughts about when life first arose on earch, and drastically narrowed the interval between formation of the planet and the evolution of life.]

LUCA, in other words, had to have been a hard-bitten little extremophile of some kind or other. And while the debate rages as to precisely what sort of entity this common ancestor was, and which of the three current domains it was more kindred to, scientists have now discovered a variety of examples of what it might have been, now thriving all over the earth -- decidedly uncuddly, extremophilic creatures sometimes called superbugs. There are, for instance, the acidophiles -- bacteria that have been found to thrive on the gas given off by raw sewage and that both excrete and multiply in concentrations of acid strong enough to dissolve metal and destroy entire city sewer systems. At the opposite end of the spectrum, there are superbugs that live in temperatures below -320 degrees Fahrenheit, lower than that of liquid nitrogen.

[jf: Recent NASA research has isolated bugs that live off the energy from aluminum ions and can survive high levels of gamma radiation and probably vacuum. It's likely we've already seeded Mars with some these bugs. Some of these terrestrial (whatever that means) bugs could not be detected by any technology we're likely to put on a space probe.]

... As far along the path toward origins as the analysis of DNA on earth has already led us, many astrobiologists say it isn't nearly far enough. Indeed, an entity like LUCA, for all its mysteries, is generally considered to be something eminently knowable, a relative latecomer in life's story, which must have had a fairly sophisticated genome to have survived the extreme conditions of the early earth. If LUCA is the common ancestor of life as we currently recognize it, the big question is: What came before that?

Many scientists now argue that before LUCA and the emergence of our current DNA-protein world, there was what's referred to as an RNA world, one made up only of rudimentary RNA-based entities that were later subsumed into RNA's current role as our DNA's messenger. And before the RNA-world, there has to have been what might be described as the real prize for astrobiologists, the so-called first living organism, or FLO.

In order to find FLO, astrobiologists must first arrive at a working definition of ''living.'' ''It all depends on what we mean by biology,'' says Jeffrey Bada, a geochemist at the Scripps Institution of Oceanography at U.C. San Diego. ''For me, I would say that all you need to define life is imperfect replication. That's it. Life. And what that means is that the entity can make copies of itself but not exact copies. A perfectly replicating system isn't alive because it doesn't evolve [jf. So really Bada is defining life as a "contained system capable of evolution" -- by that definition the world economy is "alive". I've made the same point -- canopy economics.] Quartz crystals make exact copies of themselves and have done from the beginning of the earth. They don't evolve, however, because they're locked into that particular form. But with imperfect replication you get mutants that develop some sort of selective advantage that will allow them to dominate the system.

... What is known about FLO is that for it to have happened at all, it had to have been an even tougher entity than LUCA was merely to overcome the universe's most prohibitive law, the second law of thermodynamics, which dictates that all matter tends toward entropy, the dissipation of energy. All life is in utter defiance of that law, a bound, energy-gathering stay, however brief, against entropy. [jf: This has bothered physicists for a long time. Crick was a physicist by training -- it bothered him. I dimly recall it bothered Neils Bohr, Schrodinger, and their kin.]

... The other essential requirement for the kind of imperfect replication system that Bada describes is that there had to have been a first bit of information, some kind of biochemical message, or code, however crude, to begin to convey. Or, in this case, to misconvey, the whole story of life's emergence and evolution on earth being, in essence, a multibillion-year-long game of telephone, in which the initial utterance, the one that preceded all others, was increasingly transmuted and reinvented the further along it was passed. It is the precise nature of that first utterance that astrobiologists are trying to decipher.

'There are some people,'' Bada says, ''who would argue quite vigorously with me about whether the simple kind of replicators I speak of qualify as life. Others would argue that even the sorts of simpler catalytic, self-sustaining reactions that occur on mineral surfaces are living, or are the first type of living system, without even the requirement for genetic information. But to me that's still chemistry, not life. Or it's life as we don't know it.''

A number of chemists are now trying to recreate in their labs at least a rough approximation of this elusive and somewhat ill-defined transition from the purely chemical to the biological, searching for the mix of ingredients which in their interaction create ever more complex molecules in a recurring series of feedback loops that eventually culminate in a self-replicating system that soon dominates its environment. Gerald Joyce, a colleague of Bada's at U.C. San Diego, and one of the pioneers of test-tube evolution, has managed to achieve such a synthesis in his lab using a random mixture of RNA molecules. Jack Szostak of the Harvard Medical School, meanwhile, has been doing groundbreaking work in his lab with organic compounds known as amphiphiles -- compounds that have been shown to produce in water cell-like structures known as vesicles, the ideal sort of contained microenvironment that the earliest living entity on earth might have needed to get started.

''I'm going to stick my neck out here,'' Bada says, ''but I'd be surprised, very surprised, if in the next 5 or 10 years somebody somewhere doesn't make a molecular system that can self-replicate with very little interaction on our part. You just give it the proper chemicals and it starts churning away and replicates and growing and soon dominates the system.'' [jf. Sounds like a "New Kind of Science"?]

... The early earth is now thought to have had a number of different atmospheres over the long course of its coalescence, the most likely was a rather bland mix of nitrogen and carbon dioxide, one not highly conducive to the production of amino acids. Meanwhile, amino acids have been discovered just about everywhere, including inside meteorites and, evidence suggests, drifting about in the so-called interstellar medium. [jf. I thought the BBC recently reported clouds of simple carbohydrates in extrasolar space, but I can't find the article now. Update: it was a cloud of simple sugar molecules in our galaxy.]

... long with carbon and a number of other organic compounds essential to life, amino acids seem to have come along with the universe's original package, woven into the very fabric of our solar system and perhaps long before that, hailing from somewhere out there in that vast 10-billion-year lacuna between the Big Bang and the earth's debut. In the words of Jill Tarter, an astrobiologist at the SETI Institute: ''Every atom of iron in our blood was produced in a star that blew up about 10 billion years ago.'' What those searching the heavens for the answer to life's origins are trying to decipher is how these seemingly prepackaged ingredients for life actually became life, and whether our planet could possibly have been the only viable egg in the universe's sack.

... Even the decidedly low-key Sandford starts twisting in his seat like an excited kid on Christmas morning when he thinks about the return of the Stardust capsule in January 2006, and the possible secrets buried therein. Once the material is recovered, certain tests conducted on whatever organic compounds are found will both certify their extraterrestrial origin and perhaps ultimately help to determine their approximate age in relation to the formation of our solar system and of the earth.

''We want to try to get a real sense of what kinds of building blocks are out there that arrive on planets on Day 1 of their formation,'' says Sandford. ''Of course, since we don't know how exactly life got started, it's hard to assess how critical each compound is. Even if life is an inevitable byproduct of stuff falling out of the sky, certain key aspects of life's formation may also be dominated by indigenous activity on a given planet. Life may have had to beg and borrow and steal everything it could get to happen, and so why be picky? For a long time the argument about origins has been an either-or type of thing: life either happened with a bolt of lightning to the early atmosphere or it was the opposite extreme of actual bugs falling out of the sky and seeding the earth. The truth probably falls somewhere in the middle of that.''

... a number of other astrobiological starcombers have their sights and hopes set on a mission the results of which neither they nor many of us alive today will be around to witness: landing upon and drilling into Jupiter's moon Europa.

About the size of the earth's moon, Europa is covered by ice roughly 6 miles deep, beneath which is 30 to 60 miles of water, roughly the same volume as that of the earth's oceans. While water is often thought to be synonymous with life, Europa is totally dark, ruling out any form of photosynthesis, and thus life as we understand it. There is also thought to be little or no communication between the underlying ocean and Europa's surface. All of which makes the prospect of discovering any signs of life there almost unbearably enticing to astrobiologists.

''I'd love nothing more than for us to find a thriving RNA world there,'' says Bada. ''We can try to reconstruct that in a lab, but if we had a natural example of it, that would be fantastic. We'd have a picture of what life may have been like on earth before it evolved into the modern protein-DNA world of today. Of course, it's hard to imagine the kind of environment that's on Europa producing organisms that look anything like the biochemistry we have here, either modern or LUCA-type organisms. And that's what I find fascinating. Here we could have a completely independent form of life, even though the chemistry leading up to it might be universal. Now, I don't expect little green men to crawl out of the ocean there, but I wouldn't be a bit surprised if we didn't see some extremely interesting chemistry involved in some of the very stages that led to replicating entities here on earth.''

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Phew. A relief from thinking about our negligent and incompetent government!

A parting thought. If it turns out that the fundamental physics of the universe predispose to a cloud of life forming soup infesting all of space, what does that say about the "design" of the universe? And Fermi's Paradox?

Organizers Fear Terrorist Attacks On Upcoming Al-Qaeda Convention

The Onion | Organizers Fear Terrorist Attacks On Upcoming Al-Qaeda Convention

The al-Qaeda International Convention will open Friday with a keynote speech from Zell Miller, the Democratic senator from Georgia who raised hackles by throwing his support behind al-Qaeda during this year's election.

Where were the WMDs? An insider's summary -- relatively objective?

The New York Times > Opinion > MAHDI OBEIDI: Saddam, the Bomb and Me

The emphases below are mine. I find this fascinating in many dimensions. It agrees with my prejudices, but adds some new agnles.

While the final report from Charles A. Duelfer, the top American inspector of Iraq's covert weapons programs, won't be released for a few weeks, the portions that have already been made public touch on many of the experiences I had while working as the head of Saddam Hussein's nuclear centrifuge program. Now that I am living in the United States, I hope to answer some of the most important questions that remain.

What was really going in Iraq before the American invasion last year? Iraq's nuclear weapons program was on the threshold of success before the 1991 invasion of Kuwait - there is no doubt in my mind that we could have produced dozens of nuclear weapons within a few years - but was stopped in its tracks by United Nations weapons inspectors after the Persian Gulf war and was never restarted. During the 1990's, the inspectors discovered all of the laboratories, machines and materials we had used in the nuclear program, and all were destroyed or otherwise incapacitated.

By 1998, when Saddam Hussein evicted the weapons inspectors from Iraq, all that was left was the dangerous knowledge of hundreds of scientists and the blueprints and prototype parts for the centrifuge, which I had buried under a tree in my garden.

In addition to the inspections, the sanctions that were put in place by the United Nations after the gulf war made reconstituting the program impossible. During the 1980's, we had relied heavily on the international black market for equipment and technology; the sanctions closed that avenue.

Another factor in the mothballing of the program was that Saddam Hussein was profiting handsomely from the United Nations oil-for-food program, building palaces around the country with the money he skimmed. I think he didn't want to risk losing this revenue stream by trying to restart a secret weapons program.

Over the course of the 1990's, most of the scientists from the nuclear program switched to working on civilian projects or in conventional-weapons production, and the idea of building a nuclear bomb became a vague dream from another era.

So, how could the West have made such a mistaken assessment of the nuclear program before the invasion last year? Even to those of us who knew better, it's fairly easy to see how observers got the wrong impression. First, there was Saddam Hussein's history. He had demonstrated his desire for nuclear weapons since the late 1970's, when Iraqi scientists began making progress on a nuclear reactor. He had used chemical weapons against his own people and against Iran during the 1980's. After the 1991 war, he had tried to hide his programs in weapons of mass destruction for as long as possible (he even kept my identity secret from weapons inspectors until 1995). It would have been hard not to suspect him of trying to develop such weapons again.

The Western intelligence services and policy makers, however, overlooked some obvious clues. One was the defection and death of Saddam Hussein's son-in-law, Hussein Kamel, who was in charge of the unconventional weapons programs in the 1980's.

As my boss, Mr. Kamel was a brutal taskmaster who forced us to work under impossible deadlines and was the motivating force for our nuclear effort. The drive for nuclear weapons began in earnest when he rose to a position of power in 1987. He placed a detail of 20 fearsome security men on the premises of our centrifuge lab, and my staff and I worked wonders just to stay out of his dungeons. But after he defected to Jordan in 1995, and then returned months later only to be assassinated by his father-in-law's henchmen, the nuclear, chemical and biological weapons programs lost their top promoter.

In addition, the West never understood the delusional nature of Saddam Hussein's mind. By 2002, when the United States and Britain were threatening war, he had lost touch with the reality of his diminished military might. By that time I had been promoted to director of projects for the country's entire military-industrial complex, and I witnessed firsthand the fantasy world in which he was living. He backed mythic but hopeless projects like one for a long-range missile that was completely unrealistic considering the constraints of international sanctions. The director of another struggling missile project, when called upon to give a progress report, recited a poem in the dictator's honor instead. Not only did he not go to prison, Saddam Hussein applauded him.

By 2003, as the American invasion loomed, the tyrant was alternately working on his next trashy novel and giving lunatic orders like burning oil around Baghdad to "hide" the city from bombing attacks. Unbelievably, one of my final assignments was to prepare a 10-year plan for military-industrial works, even as tens of thousands of troops were gathering for invasion.

To the end, Saddam Hussein kept alive the Iraqi Atomic Energy Commission, staffed by junior scientists involved in research completely unrelated to nuclear weapons, just so he could maintain the illusion in his mind that he had a nuclear program. Sort of like the emperor with no clothes, he fooled himself into believing he was armed and dangerous. But unlike that fairy-tale ruler, Saddam Hussein fooled the rest of the world as well.

Was Iraq a potential threat to the United States and the world? Threat is always a matter of perception, but our nuclear program could have been reinstituted at the snap of Saddam Hussein's fingers. The sanctions and the lucrative oil-for-food program had served as powerful deterrents but world events - like Iran's current efforts to step up its nuclear ambitions - might well have changed the situation.

Iraqi scientists had the knowledge and the designs needed to jumpstart the program if necessary. And there is no question that we could have done so very quickly. In the late 1980's, we put together the most efficient covert nuclear program the world has ever seen. In about three years, we gained the ability to enrich uranium and nearly become a nuclear threat; we built an effective centrifuge from scratch, even though we started with no knowledge of centrifuge technology. Had Saddam Hussein ordered it and the world looked the other way, we might have shaved months if not years off our previous efforts.

So what now? The dictator may be gone, but that doesn't mean the nuclear problem is behind us. Even under the watchful eyes of Saddam Hussein's security services, there were worries that our scientists might escape to other countries or sell their knowledge to the highest bidder. This expertise is even more valuable today, with nuclear technology ever more available on the black market and a proliferation of peaceful energy programs around the globe that use equipment easily converted to military use.

Hundreds of my former staff members and fellow scientists possess knowledge that could be useful to a rogue nation eager for a covert nuclear weapons program. The vast majority are technicians who, like the rest of us, care first about their families and their livelihoods. It is vital that the United States ensure they get good and constructive jobs in postwar Iraq. The most accomplished of my former colleagues could be brought, at least temporarily, to the West and placed at universities, research labs and private companies.

The United States invaded Iraq in part to end what it saw as a nuclear danger. It is now vital to reduce the chance of Iraq's dangerous knowledge spilling outside of its borders. The nuclear dangers facing the world are growing, not decreasing. My hope is that the Iraqi example can help people understand how best to deal with this threat.

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Let's count the insights.

1. The sanctions worked. (They were collapsing though, both France and Russia wanted to abandon them.)
2. Western intelligence missed the large role of Kamel, an evil man who met an evil death at the hands of an evil man.
3. It takes about 4-5 years for a nation like Iraq to build a nuclear weapon. That's supposedly without Khan's help. Post-Khan I'd guess two years. I think that makes "containment" all but impossible. I wonder how long ago US intelligence decided that containment would no longer work.
4. He hid the centrifuge parts under a tree. So when were they found? By whom?
5. Saddam really was insane by the end of his reign.
6. The 'Oil for Food' bribes had a bright side. They incented Saddam to keep the sanctions going.
6. For Iraq the reasoning is simple. Iran has a bomb, therefore Iraq must have a bomb. This reasoning applies irregardless of who Iraq's tyrant is. It will be ironic if America's tyrant completes the program Saddam began.

The state of Iraq -- worse than was ever imagined, and getting worse yet

War and Piece

The diplomatic editor if the UK Times is, incredibly, still in Baghdad. He writes a description of life there. It's a bit different from the fantasy American's are ingesting.

Kerry finds his honest voice

Shrillblog: Yet Another Member of the Shrill

The administration told us we’d be greeted as liberators. They were wrong. They told us not to worry about looting or the sorry state of Iraq's infrastructure. They were wrong. They told us we had enough troops to provide security and stability, defeat the insurgents, guard the borders and secure the arms depots. They were wrong. They told us we could rely on exiles like Ahmed Chalabi to build political legitimacy. They were wrong. They told us we would quickly restore an Iraqi civil service to run the country and a police force and army to secure it. They were wrong. In Iraq, this administration has consistently over-promised and under-performed. This policy has been plagued by a lack of planning, an absence of candor, arrogance and outright incompetence. And the President has held no one accountable, including himself. In fact, the only officials who lost their jobs over Iraq were the ones who told the truth.

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I've seen the electoral college projections. Barring a miracle, Kerry has lost this election -- and so has America. There's no claim for innocence here -- every voter who cared a whit had the evidence in front of them.

It's too bad the world has to suffer for our failings.

At least Kerry will go down swinging hard. He must feel at this point that he has nothing to lose. He may wish History to testify that he spoke truth to power.

PSA. HRT. SSRIs. Houston, we have a problem.

News

Professor Stamey first suggested that a blood test for prostate-specific antigen (PSA) could indicate the presence of cancer in a paper in The New England Journal of Medicine in 1987. The discovery spawned a vast prostate screening industry - nearly a quarter of a million men will be diagnosed with prostate cancer in the US this year - and a huge growth in the number of men treated for the condition. Now, he has recanted, and suggests that the test merely indicates the size of the prostate and may do more harm than good by encouraging over-treatment. Many of the cancers detected by it are too small to be clinically meaningful and many men may have been unnecessarily treated. 'The PSA era is over,' he said in The Journal of Urology.

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Ten years ago, when I was actively practicing medicine, I was among those on the front line who were very unsure about the value of the PSA test. I give full credit to my internist colleagues for their deep and abiding suspicion of the PSA. Then Dear Abby/Ann began pushing it, then Bob Dole, then resistance became futile.

Now it looks bad for the PSA.

Hormone Replacement Therapy had a similar path. SSRIs are looking shaky -- primarily because an emergent (unconscious?) de facto collusion between manufacturers, researchers, academics and publishers produced a biased publication base. (One UK researcher clinician emerges as a hero in the SSRI debacle -- a lesson about the need to resuscitate the dying breed of clinician-researcher.)

Medicine has a problem. I think it's a research funding, tenure, promotion and publication problem, compounded by issues with professional identity and severe stress and distress among primary care physicians. The situation isn't quite hopeless; some of the steps being taken with electronic publication (advertising free!) and clinical trials registrations are very important. I think we need the AHRQ to be fully alive again -- it was badly wounded about 10 years ago by an unfortunate alliance between libertarian ideologues, anti-science politicians and fearful subspecialists. Maybe orthopods could do penance by resuscitating the AHRQ.

The younger George Bush

Salon.com News | The dunce

Recollections of a GWB business school prof:

Students who challenged and embarrassed Bush in class would then become the subject of a whispering campaign by him, Tsurumi said. "In class, he couldn't challenge them. But after class, he sometimes came up to me in the hallway and started bad-mouthing those students who had challenged him. He would complain that someone was drinking too much. It was innuendo and lies. So that's how I knew, behind his smile and his smirk, that he was a very insecure, cunning and vengeful guy." ...

"I used to chat up a number of students when we were walking back to class," Tsurumi said. "Here was Bush, wearing a Texas Guard bomber jacket, and the draft was the No. 1 topic in those days. And I said, 'George, what did you do with the draft?' He said, 'Well, I got into the Texas Air National Guard.' And I said, 'Lucky you. I understand there is a long waiting list for it. How'd you get in?' When he told me, he didn't seem ashamed or embarrassed. He thought he was entitled to all kinds of privileges and special deals. He was not the only one trying to twist all their connections to avoid Vietnam. But then, he was fanatically for the war."

Tsurumi told Bush that someone who avoided a draft while supporting a war in which others were dying was a hypocrite. "He realized he was caught, showed his famous smirk and huffed off."

Tsurumi's conclusion: Bush is not as dumb as his detractors allege. "He was just badly brought up, with no discipline, and no compassion," he said.

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Apparently Bush demonstrated even then a remarkable facility for the bald faced lie. It is his genius.

Senior US military leaders speak-up: Bush has brought us to unprecedented disaster

Guardian Unlimited | Sidney Blumenthal | Far graver than Vietnam

Or, as I've been saying lately, rather like Checknya with oil.

...But, according to the US military's leading strategists and prominent retired generals, Bush's war is already lost. Retired general William Odom, former head of the National Security Agency, told me: "Bush hasn't found the WMD. Al-Qaida, it's worse, he's lost on that front. That he's going to achieve a democracy there? That goal is lost, too. It's lost." He adds: "Right now, the course we're on, we're achieving Bin Laden's ends."

Retired general Joseph Hoare, the former marine commandant and head of US Central Command, told me: "The idea that this is going to go the way these guys planned is ludicrous. There are no good options. We're conducting a campaign as though it were being conducted in Iowa, no sense of the realities on the ground. It's so unrealistic for anyone who knows that part of the world. The priorities are just all wrong."

Jeffrey Record, professor of strategy at the Air War College, said: "I see no ray of light on the horizon at all. The worst case has become true. There's no analogy whatsoever between the situation in Iraq and the advantages we had after the second world war in Germany and Japan."

W Andrew Terrill, professor at the Army War College's strategic studies institute - and the top expert on Iraq there - said: "I don't think that you can kill the insurgency". According to Terrill, the anti-US insurgency, centred in the Sunni triangle, and holding several cities and towns - including Fallujah - is expanding and becoming more capable as a consequence of US policy.

"We have a growing, maturing insurgency group," he told me. "We see larger and more coordinated military attacks. They are getting better and they can self-regenerate. The idea there are x number of insurgents, and that when they're all dead we can get out is wrong. The insurgency has shown an ability to regenerate itself because there are people willing to fill the ranks of those who are killed. The political culture is more hostile to the US presence. The longer we stay, the more they are confirmed in that view."

After the killing of four US contractors in Fallujah, the marines besieged the city for three weeks in April - the watershed event for the insurgency. "I think the president ordered the attack on Fallujah," said General Hoare. "I asked a three-star marine general who gave the order to go to Fallujah and he wouldn't tell me. I came to the conclusion that the order came directly from the White House." Then, just as suddenly, the order was rescinded, and Islamist radicals gained control, using the city as a base.

"If you are a Muslim and the community is under occupation by a non-Islamic power it becomes a religious requirement to resist that occupation," Terrill explained. "Most Iraqis consider us occupiers, not liberators." He describes the religious imagery common now in Fallujah and the Sunni triangle: "There's talk of angels and the Prophet Mohammed coming down from heaven to lead the fighting, talk of martyrs whose bodies are glowing and emanating wonderful scents."

"I see no exit," said Record. "We've been down that road before. It's called Vietnamisation. The idea that we're going to have an Iraqi force trained to defeat an enemy we can't defeat stretches the imagination. They will be tainted by their very association with the foreign occupier. In fact, we had more time and money in state building in Vietnam than in Iraq."

General Odom said: "This is far graver than Vietnam. There wasn't as much at stake strategically, though in both cases we mindlessly went ahead with the war that was not constructive for US aims. But now we're in a region far more volatile, and we're in much worse shape with our allies."

Terrill believes that any sustained US military offensive against the no-go areas "could become so controversial that members of the Iraqi government would feel compelled to resign". Thus, an attempted military solution would destroy the slightest remaining political legitimacy. "If we leave and there's no civil war, that's a victory."

General Hoare believes from the information he has received that "a decision has been made" to attack Fallujah "after the first Tuesday in November. That's the cynical part of it - after the election. The signs are all there."

He compares any such planned attack to the late Syrian dictator Hafez al-Asad's razing of the rebel city of Hama. "You could flatten it," said Hoare. "US military forces would prevail, casualties would be high, there would be inconclusive results with respect to the bad guys, their leadership would escape, and civilians would be caught in the middle. I hate that phrase collateral damage. And they talked about dancing in the street, a beacon for democracy."

General Odom remarked that the tension between the Bush administration and the senior military officers over Iraqi was worse than any he has ever seen with any previous government, including Vietnam. "I've never seen it so bad between the office of the secretary of defence and the military. There's a significant majority believing this is a disaster. The two parties whose interests have been advanced have been the Iranians and al-Qaida. Bin Laden could argue with some cogency that our going into Iraq was the equivalent of the Germans in Stalingrad. They defeated themselves by pouring more in there. Tragic.

Slate - Does God endorse George Bush?

Heaven Sent - Does God endorse George Bush? By Steven Waldman

Of course, it's always possible God did put George W. Bush in the White House. But if He did, it doesn't theologically follow that He wants him to have a second term.

Where is George Bush's genius?

Brad DeLong's Semi-Daily Journal: A Weblog: Wow! Francis Fukuyama Is Shrill!

George Bush must have a peculiar genius. He couldn't have gotten where he is without a fantastic gift.

It's not his raw IQ. Based on his SAT scores his raw IQ is probably about 120. Average to above average for college.

It's not his insight, wisdom or judgment. Those have been catastrophic.

It's not his choice of allies. Cheney? Rumsfeld?

And yet ...

He has many followers. He exerts iron control over many who are far more capable, in naive terms, than he.

My guess he has a genius for four related things:

1. Lying. I think he has a capacity for deception beyond everyday imaging. I would NEVER play poker against George Bush.

2. Raw leadership -- the peculiar gene that persuades others that he should be followed, that he is competent and wise.

3. The ability to project the appearance of wisdom, confidence, and considered judgment.

4. Rewarding his allies and punishing his enemies -- thereby imposing an iron loyalty and discipline. This requires the an incredible capacity to carry a grudge.

Combine the above with an insatiable lust for power over others, and we have a recipe for disaster -- GWB, father of the American Chechnya.

Iraq is not Vietnam....

Back to Iraq ...

I had one of those nasty revelations last night, on reading an Economist article on the state of Chechnya. It's obvious in retrospect, and I'm sure it's a common observation everywhere in the world ... except in America.

We've been blinded by our history in Vietnam. So blinded we've chosen the wrong lens for viewing our predicament.

Iraq is not Vietnam.

It is Chechnya.

Back to Iraq 3.0: It's Worse Than You Think...

Back to Iraq 3.0: It's Worse Than You Think...

Anyone who asks me to tell the “real” story of Iraq — implying all the bad things are just media hype — should refer to this post. I just told you the real story: What was once a hell wrought by Saddam is now one of America’s making.

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This guy was once a relatively optimistic observer. I think he might once have been Republican, or at least an independent.

It sounds like we've lost. Bush, Rumsfeld and their kin have cost us, and Iraq, so very, very much.

Rumsfeld and Fallujah

Key General Criticizes April Attack In Fallujah (washingtonpost.com): "The comments by Lt. Gen. James T. Conway, made shortly after he relinquished command of the 1st Marine Expeditionary Force on Sunday, amounted to a stinging broadside against top U.S. military and civilian leaders who ordered the Fallujah invasion and withdrawal."

Rumsfeld "termination justification" file is about six inches thick.

The Shrill Blog: Martin Sieff Scores the Neocons at Zero for Twenty-One

The Shrill Blog: Martin Sieff Scores the Neocons at Zero for Twenty-One

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These are 21 major neocon predictions that have been proven wrong.

Did they make ANY predictions that have been proven correct?

If these guys were ball players they'd have been retired by now. Instead they are making new plans.