Medical fads - are they cycling faster?

We've always had crazy fads in medicine.

I fell for a few when I had wet ears. Magnesium Sulfate post-MI is the one I remember best. That one even made it to textbooks before it died.

It's typical of medical fads that they infest journals, and now newspapers, but usually die before they get to textbooks. Estrogen for osteoporosis wasn't in that class -- that was a somewhat understandable research problem. Medical fads are less forgivable; they really aren't supported by evidence. They're built on easy money and bored specialists.

It feels like the fads are cycling faster. Emily and I thought the Vitamin D craze had another year or two, but it died fast.

Our local minor neurotrauma ("acute mild head injury") craze reeks of fadism. In Minnesota recommendations are being written into law, with little basis in science. As of today, PubMed has precious few studies.

Maybe it will be real. Some cults become established religions, some fads become science.

I don't think this one will make it to science, I do think it will cause significant harm along the way. Labels are powerful.

Hope this cycles as fast as Vitamin D, but putting minor traumatic brain injury into law may stretch its lifespan. Medical fadism is a crime against the vulnerable...

Update: More on the Vitamin D fad.

A few readers asked me for more detail on the vitamin D fad.

Briefly, for a year or two, I couldn't avoid popular articles claiming that Americans suffered from an epidemic of Vitamin D deficiency causing a wide range of disorders, and that recommended daily allowances were inadequate. Then, at the end of 2010, the Institute of Medicine published a report declaring that the science wasn't there, and that overdosing was more harmful than expected ... (emphases mine)

... The committee provided an exhaustive review of studies on potential health outcomes and found that the evidence supported a role for these nutrients in bone health but not in other health conditions. Overall, the committee concludes that the majority of Americans and Canadians are receiving adequate amounts of both calcium and vitamin D. Further, there is emerging evidence that too much of these nutrients may be harmful...

In retrospect, within a few months of the IOM report, the media attention ended. The fad moved on.

There's still science to be done of course. Ever since medical school I've wondered about the relationship of latitude to multiple sclerosis, and whether there was some kind of cutaneous immunity/solar radiation component. Today there are many interesting articles on the relationship between vitamin D and MS. That's research though, the fad is over.

Finance 2.0, Oil and Project Syndicate - entertainment 2012!

My, oh, my, it's still a whitewater world.

Ezra Klein tells us ...

America’s top export in 2011 is refined fuel ...

... UC San Diego economist James Hamilton ...  the glut of new shale oil in North Dakota. Since there’s not enough pipeline infrastructure to get all that oil down to the Gulf of Mexico for export, it’s been piling up in Cushing, Okla. That makes it cheap for refineries in the Midwest to refine it and ship it out than to simply ship the oil directly...

Brad Delong tells us that the business of America is Finance (8.4%, healthcare is about 17%, emphases mine) ...

America’s Financial Leviathan - J. Bradford DeLong - Project Syndicate

... In 1950, finance and insurance in the United States accounted for 2.8% of GDP, according to US Department of Commerce estimates. By 1960, that share had grown to 3.8% of GDP, and reached 6% of GDP in 1990. Today, it is 8.4% of GDP, and it is not shrinking. The Wall Street Journal’s Justin Lahart reports that the 2010 share was higher than the previous peak share in 2006....

... it remains disturbing that we do not see the obvious large benefits, at either the micro or macro level, in the US economy’s efficiency that would justify spending an extra 5.6% of GDP every year on finance and insurance. Lahart cites the conclusion of New York University’s Thomas Philippon that today’s US financial sector is outsized by two percentage points of GDP. And it is very possible that Philippon’s estimate of the size of the US financial sector’s hypertrophy is too small.

Why has the devotion of a great deal of skill and enterprise to finance and insurance sector not paid obvious economic dividends? There are two sustainable ways to make money in finance: find people with risks that need to be carried and match them with people with unused risk-bearing capacity, or find people with such risks and match them with people who are clueless but who have money. Are we sure that most of the growth in finance stems from a rising share of financial professionals who undertake the former rather than the latter?

Perhaps, then, what we need are 'heroes' who can separate foolish rich people from their money?

Saudi America and Finance still amuck; this world would be more entertaining if we didn't live in it.

Speaking of entertainment, Brad's post was the first I'd heard of Project Syndicate ...

Project Syndicate - the highest quality op-ed articles, analysis and commentaries

... Project Syndicate: the world's pre-eminent source of original op-ed commentaries. A unique collaboration of distinguished opinion makers from every corner of the globe, Project Syndicate provides incisive perspectives on our changing world by those who are shaping its politics, economics, science, and culture. Exclusive, trenchant, unparalleled in scope and depth: Project Syndicate is truly A World of Ideas. As of December 2011, Project Syndicate membership included 477 leading newspapers in 151 countries. Financial contributions from member papers in advanced countries support the services provided by Project Syndicate free of charge or at reduced rates to members in developing countries. Additional support comes from the Open Society Institute...

Lots of the usual suspects there .... Bhagwati, DeLong, Rogoff, Robini, Stiglitz, Joseph Nye, Jeffrey Sachs, and many more names I should probably know. It's not new, Google Reader went back to 10/2010, and there are series posts from 2008. They don't seem to be marketing very seriously.

I don't see any way to explore their archives by date. It's darkly amusing to read Nouriel Roubini's predictions on the Great Recession at the end of 2008 ...

Will Banks and Financial Markets Recover in 2009? - Nouriel Roubini - Project Syndicate

The United States will certainly experience its worst recession in decades, a deep and protracted contraction lasting about 24 months through the end of 2009. Moreover, the entire global economy will contract. There will be recession in the euro zone, the United Kingdom, Continental Europe, Canada, Japan, and the other advanced economies. There is also a risk of a hard landing for emerging-market economies, as trade, financial, and currency links transmit real and financial shocks to them...

... 2009 will be a painful year of global recession and further financial stresses, losses, and bankruptcies. Only aggressive, coordinated, and effective policy actions by advanced and emerging-market countries can ensure that the global economy recovers in 2010, rather than entering a more protracted period of economic stagnation.

The NBER tells us the US left recession in June 2009, though this is a technical determination. I suspect most Americans feel we're still in a recession.

Good thing I don't have enough to read.

Update: Browsing Project Syndicate, I'm finding a fair bit of pompous nonsense (Naomi Wolf?!). I'll probably have to subscribe to individual contributors.

I win Apple's Nano recall lottery

LiOn battery issues (burst into flame!) have led to an Apple recall of the 1st generation iPod Nano. I dug out my neglected Nano and sent it to Apple in early November. I wasn't using it, but it is a good match to the gym. I figured I'd at least get a new battery. Apple announced they weren't going to replace them with new devices, just replace the battery.

Weeks went by. I began to wonder what was up; past recalls were processed very quickly.

Today it showed up -- but it was now an 8GB $130 6th generation Nano. It is a sweet device, even though it's an impractical wristwatch. A very nice improvement on the 1st generation; easy to clip to clothing, radio, more capacity, etc.

I think Apple did start out returning the original Nano, so I can't promise that won't happen in the future. It may be Apple got so backlogged on repairs that they decided they needed to ship something. Or perhaps the opportunity cost of the tedious repairs was balanced against the customer satisfaction of sending a vastly better replacement.

That would fit my recent experiences with Apple service, including iTunes Apple Store errors (all my problem, not Apple's) and an out of warranty iMac repair. Apple service used to be merely better than the competition, but I think they've kicked it up a notch. Talk about crushing the competition.

It would be very nice if customer service were to rise from the dead across the economy. Retailers do follow Apple now ...

GOP 2.0: What rational climate change politics might look like

"With great power comes great responsibility." Gingrich's inner geek smiled at that one. Certainly they had the power. The Democrats had been crushed by the 2012 elections. President Romney now controlled the House, the Senate and the Supreme Court -- and the filibuster had been eliminated in early 2013.

Gingrich was philosophical about the Vice Presidency; Cheney had taught him what could be done. Romney was happy enough to hand off the big one to him.

Not health care of course. That had been a trivial problem; it took only a few months to tweak ObamaCare, throw in some vouchers and a few distractions, and launch RomneyCare. The GOP base was fine with rebranding, and the dispirited remnant of the Democrats saw little real change.

No, the big one was climate change. Romney and Gingrich had never truly doubted that human CO2 emissions were driving global climate change, but pivoting the base took a bit of work. They'd begun with ritual purges; Hansen was quickly exiled to the lecture circuit. Then came the American Commission on Truth in Science. There wasn't even much tormenting of old enemies; the size of the GOP victory had taken the fun out of that. In short order the "weak mindedness" of the Democrats was exposed and the "honest and rigorous" examination of the Romney administration was completed. It was time, Murdoch's empire declared, for strong minded Americans to face hard (but not inconvenient) facts.

The hardest challenge came from a contingent that felt global warming was a good thing, even God's plan. American drought was weakening that group, but they were a constant headache.

Now though it was time for policy, and Gingrich couldn't be happier. He'd been meeting with Bill Clinton of course; the two rogues loved the evening debates. Clinton's engagement wasn't just for fun, despite the GOP's dominance there was still room for politics. America's wealthy had been irrationally terrified of Obama, but they were also afraid of runaway warming -- and they had considerable power. Trillions of dollars were at stake in any real attack on global warming, and every corporation in America was at the door. The Military was pushing for aggressive management. Lastly, Gingrich knew that power can shift. He'd seen it before.

He wrote out the options, and labeled them by their natural political base ...

• Climate engineering: solar radiation reduction, massive sequestration projects (R)
• CO2 pricing (by hook or crook) (R/D - political debate is how revenues are used)
• Subsidies for public transit (D)
• Urban planning measures (D)
• Military strategy to manage anticipated collapse of African nations (R)
• Military strategy to manage anticipated climate engineering conflicts with China (climate wars) (R)
• Tariff's on Chinese imports to charge China for their CO2 emissions (R/D - but probably tied to American CO2 pricing)
• Massive investments in solar power and conservation technologies (D)
• Massive investments in fusion power (R)

The Climate Wars were particularly troublesome. There were simple things China could do, like pump massive amounts of sulfuric acid, that would alleviate the disaster their scientists had predicted. These measures, however, would be disastrous for the US. On the other hand, war with China was unthinkable.

Gingrich new he had to put a price on Carbon and he had to get China to avoid the most dangerous (for the US) forms of climate engineering. The rest was in play. This was what Great Men were made for ...

See also:

Gordon's Notes

• Why is the modern GOP crazy? 7/2011
• Denialists in favor of a warmer earth 6/2011: This is a common GOP position now - Climate change is not due to humans, it's a good thing, and God approves.
• Global warming: Doonesbury and China 9/11 - another GOP position variant, warming is relatively bad for China, relatively good for the US. This is probably true.
• Global Warming: We're scr***d. 8/2006 - it's too late anyway. Another GOP position, also partly true.
• The rational basis for climate change denialism 20/2010 - God made the earth for us, so the climate is His.
• Greece, America and GOP 2.0 12/2011
• Global climate change: it's time to think radical 9/2006 - climate engineering is coming.
• UnReason: The Republican War on Reason 2/2011
• We're crazy now. We were crazier forty years ago - 9/2010 by historic standards, we're not as crazy as we fear
• Birthers, Deathers and Truthers - the reason behind the madness 9/2009 - maybe the GOP is now in recovery?
• America 2011: exploring the boundaries of democracy and capitalism 1/2011: Democracy is not robust
• Keystone XL, carbon sequestration, and the tax in the closet 11/2011
• A taxonomy of American politics 2/2011 - where values differ, how democracy would work if the GOP recovers
• Climate Change and the Black Plague 5/2007 - disease changes will be disruptive
• Climate Change 2010: Plan B 11/2010 - a Carbon Tariff on China
• Why you should vote for the Tea Party’s coven in the century of the fruitbat 10/2010 - maybe only the GOP can tackle climate issues
• Separated at birth: alternative medicine and climate change denial 5/2011 - Old discussions resurface.
• Thai floods - microcosm of global climate change 11/2011 - the early and biggest impacts are outside of the US and Canada
• Science, the media and the Himalayan glacier. What's wrong? 11/2011 - scientists are cowed
• Tornados and global warming - how do we judge predictions? 5/2011 - Bayes and climate. Evidence is always probabilistic.

Others

• Shibboleths — Crooked Timber 2/2011
• The Republican War on Science by Chris Mooney - 2011 book
• Existential threats - Charlie's Diary 6/2011 - fun Stross post on existential threats. Climate change is fairly low in this ranking.
• Some things are just really hard to believe: more on choosing your facts. « Statistical Modeling, Causal Inference, and Social Science - 8/2010 - Why some things are hard to believe (roots of denialism)
• Weather as a weapon: The troubling history of geoengineering. - Slate Magazine 9/2010

Weight loss - a state of the science review

Tara Parker-Pope, who describes herself as fat, has written an excellent state-of-the-science summary on obesity in America. I've excerpted two references I particularly appreciated. The first one was discussed years ago among 'personalized medicine' conferences -- genomic information doesn't always work as expected (emphases mine) ...

The Fat Trap - Tara Parker-Pope - NYTimes.com

... In February, The New England Journal of Medicine published a report on how genetic testing for a variety of diseases affected a person’s mood and health habits. Over all, the researchers found no effect from disease-risk testing, but there was a suggestion, though it didn’t reach statistical significance, that after testing positive for fat-promoting genes, some people were more likely to eat fatty foods, presumably because they thought being fat was their genetic destiny and saw no sense in fighting it... 

... The National Weight Control Registry tracks 10,000 people who have lost weight and have kept it off. ... Anyone who has lost 30 pounds and kept it off for at least a year is eligible to join the study, though the average member has lost 70 pounds and remained at that weight for six years... 

... There is no consistent pattern to how people in the registry lost weight — some did it on Weight Watchers, others with Jenny Craig, some by cutting carbs on the Atkins diet and a very small number lost weight through surgery. But their eating and exercise habits appear to reflect what researchers find in the lab: to lose weight and keep it off, a person must eat fewer calories and exercise far more than a person who maintains the same weight naturally. Registry members exercise about an hour or more each day — the average weight-loser puts in the equivalent of a four-mile daily walk, seven days a week. They get on a scale every day in order to keep their weight within a narrow range. They eat breakfast regularly. Most watch less than half as much television as the overall population. They eat the same foods and in the same patterns consistently each day and don’t “cheat” on weekends or holidays. They also appear to eat less than most people, with estimates ranging from 50 to 300 fewer daily calories....

Most of my friends think I have never had a weight problem -- but my mother is obese. I have no trouble gaining weight, it's the easiest thing in the world. I love good bread and good french pastry (fortunately near impossible to find outside of Quebec).

What I do to control my weight is a less disciplined version of what what the "one-in-a-thousand" people in the National Weight Loss Control registry do every day of their lives. I exercise more than my peers, I eat less than my peers, and I have to watch my weight constantly. Each year I age I have to eat less. (Though I think that may plateau after age 60 or so.) The only thing I have going for me there is that I love to exercise and my knees still work. [1]

Great holiday reading :-).

[1] Note to the young - human knees are a friggin' disaster. I thank my geekiness that I never played football or even soccer. Alpine skiing is nuts. It's surprisingly hard for an active person to have good knees by age 50.

American slavery - the Bachman quote

Long ago Emily and I took a guided tour of Jefferson's home. He was described in glowing terms. In those days Jefferson was still a legend.

Historians don't think of Jefferson that way any more. He is recognized as a moral failure, a man clever enough to know the evil he lived with and too craven to deal with it. A man who sired children with his slave and left them to history's discovery.

America is very, very slowly beginning to look at slavery. Peter Birkenhead's Salon article is a minor marker of this process. It has a number of damning quotes from today's GOP, but the best of all comes from Minnesota's own Michele ...

Why we still can't talk about slavery - Civil War - Salon.com 

Once you got here, we were all the same. Isn’t that remarkable? But we also know that the very founders that wrote those documents worked tirelessly until slavery was no more in the United States.” –U.S. Rep. Michele Bachmann

Oh Michele, you are a classic.

For much more, see TNC (his book is on the way).

Peculiar consequences of wealth concentration

There is enormous, incomprehensible, wealth in the world. Increasingly, across all nations, it is concentrated in the hands of fewer and fewer people.

This has obvious consequences, but I'm sure there are surprising consequences too.

Emily and I remember a boat tour of island estates of eastern Florida. Each estate costs millions, but they were empty. Only caretakers visited, though we were told each had owners.

Owners who bought them, but had better things to do. Or maybe nothing good to do at all.

That is a problem with modern wealth. It's easy to spend a few million relatively well. Beyond that -- what is it good for? A yacht is nice if you like boats -- but then it gets boring. You can hire people to manage hassles, but then you have to manage people. A private jet? A mansion? Private artwork? Wild sex and drugs?

It would be different if we could buy lifespan -- and maybe one day that will happen. Not yet though -- at least not much if any more than the average citizen of a wealthy nation.

All that money can be used for is to play, to compete, to make more money. A game in which there is little meaning to losing, and little meaning to winning ...

Ferret flu: An existential challenge to anti-Darwinist Republicans?

The good news is that it's still hard to design a lethal plague. The 'cost of havoc' is higher than I once thought.

Yes, influenza can be weaponized by guiding Darwinian natural selection - but that takes years of patient work and advanced technologies. It's beyond the grasp of, say, Anonymous.

So this research is good news - for most of us.

Isn't it a problem for the anti-Darwinist wing of the GOP though? The group that opposes the teaching of natural selection? How do their Senators get their heads around this issue?

Greece, America and GOP 2.0

Krugman tells us Germany and the EU must bail out Greece lest the entire EU crash and burn. Germany is unenthusiastic. Michael Lewis makes Germany's lack of enthusiasm understandable ...

Amazon.com: Boomerang: Travels in the New Third World Michael Lewis

… government owed … $1.2 trillion, or more than a quarter-million dollars for every working Greek ….

… In just the past twelve years the wage bill of the Greek public sector has doubled … The average government job pays three times the average private-sector job ...

… The national railroad has annual revenues of 100 million euros against annual wage bill of 400 million ...

… The retirement age for Greek jobs classified as "arduous" is … fifty for women …

… In 2009, tax collection disintegrated, because it was an election year ...

… as estimated two thirds of Greek doctors reported incomes under 12,000 euros a year ...

…. Greece has no working national land registry ...

… all three hundred members of the Greek parliament declare the real value of their houses to be the computer-generated objective value … "every single member … is lying to evade taxes"...

Lewis describes Greece as a "perfectly corrupt society". Greece seems to have hit the limits of corruption; where the only honest people are either perversely oppositional or autistically incapable of deceit.  It's easy to see why Germany wants to put Greece through a world class social reengineering program.

Wow. Good thing we Americans aren't so corrupt. Good thing we don't have vast corporations paying no taxes. Mercifully our corporations aren't hiding trillions of dollars abroad. Our politicians don't use charitable donation scams or generate profits through insider trading that's illegal for all but Congress critters.

No way do we have the kind of widespread fraud and abuse of the weak that can lead to economic collapse.

Seriously though, if Greece is a nine on a ten point scale of democratic collapse and societal bankruptcy, how do we score? Are we a six? Do I hear a seven?

More importantly, how do we get back to a reasonable "four"? Greece is getting schooled by Germany (whose bankers were as stupid as any on earth), but nobody is going to school the US. All of Greece is barely New Orleans; we're too big to be taught.

We are going to have to reform ourselves. Occupy Wall Street can help, but to reform government we need to solve the problem of the Republican Party.

Both our political parties are corrupt, but the Dems are at least connected to science and logic. The GOP is no longer a part of the reality-based community; whatever Romney and the like may really think they have to pretend to be delusional.

We can't salvage our democracy with only one working political party. We need a reformed GOP. Some party has to do the bidding of the powerful -- lest the powerful tear the nation down. We don't need the GOP to become a shining beacon of integrity, but we do need them to be connected to logic and arithmetic and falsifiable predictions.

This isn't inconceivable. I can't imagine voting for a modern Republican, but only fifteen years ago I voted for a Republican Governor named Arne Carlson. Arne is still around, and he represents a faint voice of sanity in the modern GOP (emphases mine, note that "Pawlenty" is considered a "moderate" by modern GOP standards, but to Carlson he's a far right extremist) ...

MinnPost - Gov. Arne Carlson Blog: Bedford Falls or Pottersville?

... the Republican Party went from moderate to what I call “the new Right”. But it was more than a shift in political philosophy. Leaders like Sutton and Pawlenty and numerous others saw the party as representing not only a different and more narrow philosophy but also as having the power to rigidly enforce that philosophy on its elected members. Orthodoxy prevailed over representativeness and the result has been that cooperative governance with Democrats, Independents and Republican moderates is not possible. It is either the way of the “new Right” or not at all.

Politics is no longer a contest of competing ideas with respect for dissent but increasingly the imposition of an authoritarianism that all too often is cloaked in patriotism and religion. In this environment, the party and its beliefs are paramount and elected officials serve the party...

... my memory of Republicanism in Minnesota goes back to a party that was always building a better community … So many of our leaders came out of the progressivism of Harold Stassen while still committed to the conservative virtues of prudent financial management. Policies ranging from consumer and environmental protection to human rights to metropolitan governance bore the fingerprints of an endless array of community oriented GOP Governors from Elmer Andersen to Harold LeVander through Al Quie and on.

In addition, Republicans produced an endless array of truly talented legislators from all over Minnesota who came to our capital city to govern and always with an eye to the future. Simply put, Republicans, like their counterparts, the Democrats, felt that good politics stemmed from the competition of good ideas that produced quality governance.

And in this mix, leaders from every walk of life and every profession from medicine to agriculture participated. There seemed to be a sense of obligation to give something of oneself in order to build a better community for our children….

...The Republican Party both in Minnesota and nationally has a choice to make. Does it want to build a true Bedford Falls with a commitment to the well being of the whole or does it want to lead us to “Pottersville” where the quality of life rests with the privileged few?

We're in a bad place, but we can work our way out. Occupy Wall Street can help with some things, but they can't help with the critical mission. The critical mission is to reform the GOP; and only Republican voters can do that ...

So how do we help them?

Spider brains and the evolution of computation

Brains have a big return on investment ...

Tiniest of Spiders Are Loaded With Brains, Researchers Find - NYTimes

... In the smallest spiders, Dr. Eberhard and his colleagues found, the central nervous systems filled nearly 80 percent of the cephalothorax, or body cavity, including 25 percent of the legs.

“The brain tissue of the nervous tissue is metabolically expensive,” he said. “These little spiders are paying a very large price to keep these brains functioning.”

At times, that price includes a deformed body cavity bulging with brain matter, which may in turn compromise the size of the digestive system, Dr. Eberhard said....

Were spider brains this big 200 million years ago? Across all organisms, are brains bigger than they once were? Across all worlds, where does computation stop having positive evolutionary returns?

The "War on Chrismas" is not entirely delusional

The American "War on Christmas" movement seems thoroughly silly ....

Reminder: Tis the Season Not to Be an Ass – Whatever

...it’s about as silly as it ever was, considering that Christmas has conquered December, occupied November and metastasized into late October. To suggest that the holiday is under serious threat from politically correct non-Christians is like suggesting an earthworm is a serious threat to a Humvee. This is obvious enough to anyone with sense that I use The War on Christmas as an emergency diagnostic, which is to say, if you genuinely believe there’s a War on Christmas, you may want to see a doctor, since you might have a tumor pressing on your frontal lobes.

Seems silly, is silly.

And yet, I agree with TNC that Rick Perry is not completely delusional ...

Rick Perry and the Politics of Resentment - Ta-Nehisi Coates - Politics - The Atlantic

... What strikes me is the sense of being under siege, a constant theme in conservative politics. It is as if time itself is against them. And they know it. The line "I'm not ashamed to admit that I'm a Christian" stands out. Who is ashamed of this? This is a predominantly Christian country, and one of the most religious in the West. People don't "admit" their Christianity here. They proclaim it -- as the president has done repeatedly.

But what if there's something else? What if the conservatives are more perceptive and honest than the moderate liberals? I love Grant and Lincoln, but they were dead wrong in claiming that emancipation did not promote "social equality." Meanwhile the bigots who asserted that emancipation meant that Sambo would be "marryin yer daughters" were right. I wouldn't be shocked if Grant and Lincoln knew this, but also knew that to admit as much would be suicidal...

Yes, to most of the world the US seems to border on theocracy. But I was born into a true western theocracy, and it fell apart in less than 10 years ...

Quiet Revolution - Quebec History

The Quiet Revolution is the name given to a period of Quebec history extending from 1960 to 1966...

... The first major change that took place during the Quiet Revolution was the large-scale rejection of past values. Chief among these are those that Michel Brunet called “les trois dominantes de la pensée canadienne-française: l’agriculturisme, le messianisme et l’anti-étatisme” [the three main components of French Canadian thought: agriculturalism, anti-statism and messianism]. In this respect, Quebec entered resolutely into a phase of modernisation: its outlook became more secular (as opposed to religious), much of the traditionalism that characterised the past was replaced by increasingly liberal attitudes; long standing demographic tendencies, associated with a traditional rural way of life (high marriage, birth and fertility rates), were rapidly reversed ...

Quebec seemed stuck in the past -- until it lurched into the future. Societies can change very quickly.

Consider the case of the 2012 Presidential campaign. The GOP's presidential candidate will be theologically non-Christian (though culturally mainstream Protestant). The Dems candidate will be mainstream Protestant but raised partly in Islamic Indonesia.

That seems different, even if the current candidates aren't as theologically extreme as Jefferson, Adams or Madison. I would not be surprised if the religious attitudes of 2020 America were similar to those of 2000 Britain.

The religious right is right to be afraid, but wrong to think there's a conspiracy they can fight. Their foe is history, and it's hard to fight history. Just ask al Qaeda.

US carrier locking of post-contract iPhones - a critique

AT&T will not unlock an iPhone under any circumstances. Together with their SMS pricing this has odd results (including a glut of former iPhones).

Verizon and Sprint claim they'll allow unlocking, but the reality is more complex  (emphases mine)...

How U.S. Carriers Fool You Into Thinking Your iPhone 4S Is Unlocked - Forbes

... What consumers need to understand is that there are actually four different versions of the iPhone 4S: Verizon, Sprint, AT&T, and Apple. Only the Apple phone, available from their stores or on-line, is fully unlocked and can be used on any carrier. The other phones are permanently locked and cannot ever be used on another carrier in the U.S. Even if you spend $800 for an unlocked phone as I did and dedicate it to a single U.S. carrier, you are locked into that carrier forever if you want to keep using the iPhone. Neither Apple or the other carriers will fully unlock your carrier phone.

Apple declined to return phone calls and emails to discuss this matter. However, the high level technical support supervisor that I spoke with at length indicated that she personally thought that customers should be warned about the different versions of the phones and ramifications of buying a phone directly from a carrier rather than Apple. A senior spokesperson for Verizon told me that all Verizon phones are locked to their network and she did not quite understand the problem. I am willing to bet that Verizon customers would precisely understand this issue, even if she did not.

So if you paid retail for your iPhone 4S and purchased it from Verizon, Sprint, AT&T or Best Buy, you will never be able to use that phone with a different carrier. In my view, this is a scam by these companies. I think the cellular providers should tell their customers up front that locked phones really mean that you are locked into the carrier forever. While all of these phones are iPhone 4S with the identical hardware, the difference is that if you purchase your phone directly from Apple, it is truly a universal device and will allow you to change carriers without the penalty of making the phone worthless.

I would urge the Carriers, FCC, or Courts to enforce the following rules to protect cellular customers in the United States: consumers buying new cell phones must be informed of the existence of any SIM LOCK (also known as a network lock) on their phone before sale; wireless phone companies must unlock handsets upon request, without fee, when a consumer purchases a new phone outright (unsubsidized) without a contract; wireless phone companies must unlock handsets upon request, without fee, when a consumer comes to the end of their contract, or at any time thereafter. Carriers must fully unlock their phones (as does Apple with the iPhone 4S) and not partially unlock the phone to block access to other carriers and deny consumers the right to choose any provider anywhere...

Carrier locking of iPhones is a nasty trick on consumers. It reduces the value of a post-contract iPhone; I wonder if a clever lawyer could sue carriers for theft. Another lawyer might find the shared policies a sign of illegal collusion or price-fixing among carriers.

Senator Franken - this is right up your alley!

See also:

• Gordon's Notes: The Gordon vs. AT&T iPhone war - Conclusion (11/2011) - we dramatically cut our monthly charges.

Did canine distemper arise from measles in the new world?

(I wrote this 9/2011, but I was mistakenly left as a draft until now.)

Six years ago I read that new world dogs (canis familiaris) died in large numbers after the European invasion.

So what killed the Amerindian dog?

I assumed it was some European plague, and I suspected distemper.

I'd guess distemper. Recently I read that wild African dogs are now dying of epidemic distemper. Seems to fit. The Euros carried viruses that killed many of the native americans, it's not surprising that their dogs would have done the same thing.

Recently I read of a twist to this story

Evidence of a New World Origin for Canine Distemper -- Uhl et al. 25 (1): 613.4 -- The FASEB Journal 

.... The historical, epidemiological, paleopathological and molecular evidence supports the hypothesis that canine distemper arose in the New World from MV after the European conquest....

The Europeans brought Measles from the old world. In the new world it produced massive epidemics with astounding mortality. Tens of millions of native Americans died of Measles and other Old World diseases.

As is seen with other plagues, under these circumstances the measles virus jumped species. It went from humans to their dogs. It may have been even more lethal in the dogs of the 1500s.

Why didn't it then go back to Europe and wipe out the European dog? Did the virus adapt to its new host so it became less lethal? Could a historian who knew what to look for find evidence of massive die offs in European dogs in the 16th century?

I suspect we'll find out in the next year or two.

Syphilis - again a New World invention?

Decades ago physicians were taught that syphilis was a New World disease. The Europeans brought smallpox, and Amerindians returned syphilis. This was not a comparable exchange, smallpox and its kin killed most of the Amerindians (and another disease killed New World dogs). Syphilis, even at its worst, was not quite so deadly.

By the 1980s though, when I studied medicine, we were taught that syphilis was probably an Old World disease.

Now the pendulum has swung again ... The French Disease, the Italian Disease, the Christian Disease–the New World Disease?. Seems like it may be a New World disease after all.

See also:

• Conflagration -- the european invasion of the americas 11/2004
• History of the First Peoples - Charles Mann's 1491 11/2007
• Distemper and the death of the american dog 9/2005
• Rat plagues wipe out indigenous rats 10/2007
• Squanto and the non-Puritan non-Pilgrim "Fathers" 9/2007
• Did canine distemper arise from measles in the new world? 12/2011

Netbooks

Dell has ended their Netbook line.

That leaves Google's Chromebooks, which aren't exactly exciting.

I wasn't just a little wrong about Netbooks, I was incredibly, unbelievably, totally wrong. Again.

I mean, this is friggin' ridiculous.

What happened?

I suppose it was the pocket computer. People with iPhones and the Android equivalent are already paying for most of what a Netbook can do. It doesn't make sense to pay for an extra monthly data plan, and a Netbook without net access is kind of a bust.

That leaves Windows notebooks, which are cheap but crummy. And MacBook Airs, which are not cheap but very amazing.

There's still the grade school and perhaps junior high school marketplace, but the iPad and Android equivalents are squeezing there too.

The Netbook looks like an evolutionary dead end. Maybe we'd have taken that road, but the iPhone blew a hole in it by mid-2007. I was writing in 2009; the bloody 3G was out then!

Damnit Netbook, you made a fool of me.

See also:

• Gordon's Notes: Making better predictions: 2011/03, a precursor to this mea culpa. BTW, I also predicted China's bubble would burst before 2012. Not much time left for that to happen ...