With New Clue to How SARS Kills, Scientists Work on Treatment - New York Times
Incredible. SARS causes ARDS by binding to pulmonary angiotensin receptors; in mice administration of angiontensin converting enzyme 2 reverses this toxicity. Until last year this receptor had not been identified in lung tissue.
This has so many implications. Nobel prize work?
I still don't feel I know why the epidemic waned. My guess has been that there was a simultaneously circulating mild strain of the SARS virus that caused a conventional cold, and acted like a natural immunization program. Clinicians got sick in some SARS centers because they were so scrupulous at infection control they missed out on the benign virus.