It turns out computer modeling of epidemics suggests an alternative strategy to mass quarantine:
Science & Technology at Scientific American.com: Study Assesses Impact of "Superspreaders" of DiseaseIn Minnesota we have recent experience with a young Amish child who is, due to an immune defect, a "super spreader" of polio . The concept of "super spreader" has thus been in the news here. I suspect the simulation study is looking at more subtle super spreaders however.
... There are two ways for a population to protect itself: either everyone can act to reduce their chance of transmission--for example, by staying at home, which can throttle a country’s economy--or authorities can identify those most likely to be superspreaders, and focus their vaccination and isolation efforts on them. --Kaspar Mossman
If we do find reasonable tests to identify super spreaders, we would be well advised to think about compensating them for the inconveniences (or worse) a selective quarantine would create. As a way to manage the coming wave of epidemics , however, this is well worth researching.
 The combination of "super spreader", Polio, and unvaccinated community is potentially explosive, but fortunately our republican governor has not quite finished dismantling Minnesota's still excellent public health infrastructure.
 As humanity simultaneously travels more, congregates more, expands into Africa, and reproduces more, we become an ever richer petri dish for novel infections.