Some neuroscientists believe the female brain does badly off estrogen, and moves from better-than-male to worse-off following menopause.
Controversial? A bit.
So the idea persists is that estrogen-like drugs may have a role in Alzheimer's prophylaxis in women.
I thought this idea bit the dust two years ago, but apparently it's still around. Undoubtedly pharmas want to split off the alleged neurprotective effects of estrogen from its effects on breast tissue.