Friday, December 05, 2003

The Political Compass: How do you rank politically?

The Political Compass
This online test is produced by a UK journalist, and it's very UK like. It's fairly clear what the "right" answers are, and how an awful Republican might answer. The "wrong" answers are phrased in such a way that it's hard to imagine even GWB really getting a "bad" (authoritarian) score.

I ended up being left-libertarian. Just to the left of Jean Chretien and the right of the Dalai Lama, but about as libertarian as the Dalai Lama. So I guess I'm in happy company.

Defect rates in American justice: 10-15% in the most severe cases

Bob Herbert, NYT: Returned to Life
In an interview, Professor Protess said he initially was surprised by the number of cases he and his students encountered in which the prisoners were innocent. "I'd always thought that miscarriages of justice were an aberration and that our justice system, overwhelmingly, worked well," he said. "But I was seeing error rates of 10 to 15 percent. I was very struck by how pervasive the problem was."

I asked if he thought any innocent people had actually been executed.

"Oh, absolutely," he said. "There's just no question."

We know error rates in medicine are reasonably high. The justice system is no better, and probably worse. Any system will err to either false positive (imprisonment and/or execution) or false negative (acquittal of the guilty); justice is supposed to err to false negative (innocent until proven guilty, beyond a reasonable doubt, etc), but in the US that's not working. Instead we err towards false conviction.

I am reasonably confident that George Bush doesn't give a damn.

Thursday, December 04, 2003

Cat lovers and rare beef eaters may be easy prey for automobiles ...

BBC NEWS | Health | Eat worms - feel better
One third of Britons carry the toxoplasma parasite in their brain.

Its natural home is the cat and it's spread in cats' faeces. It can be picked up by any mammal, from rats to cattle. The main way we get it is by eating undercooked meat (which is why 80% of the French are estimated to have it, with their love of rare meat).

Once we have it we have it for life, there's no way we can get rid of it.

Research shows it somehow manipulates rats' behaviour - it makes rats attracted to cats - their natural predator, so they're more likely to be eaten by a cat and the parasite can complete its life cycle.

For years scientists thought it had no effect on our behaviour, but now the parasite's changing their minds. Recent research suggests that people with toxyplasma have slower reaction times than those without and are also more than twice as likely to be involved in a traffic accident than those who aren't carrying the parasite.

The BBC news story is a tie in to a BBC broadcast. The broadcast sounds gruesome and fascinating. I've been following the UC/hookworm studies for years and I'm looking forward to the study publications. This Toxoplasma data is new to me though, and it's rather unsettling. It's not good news for people who have pet cats or who like their meat rare. Personally, I'm switching to well done, though it may be too late for me! Good news for dog loving cat hating vegetarians though ... (I think dogs don't get toxoplasma ...)

Friday, November 28, 2003

Courage in Saudi Arabia and the next Iraqi Invasion

Op-Ed Contributor: Telling the Truth, Facing the Whip
Courage like this is breathtaking. A Saudi journalist says that Saudi Arabia must turn away from Wahhabism -- the state religion.

The weak evidence I get to read points ever more to Wahhabism as the true heart and soul of al Qaeda. If this is what the Bush administration also believes, then it supports one hypothesis about the invasion of Iraq. Namely that the Bush administration believes that sooner or later the US will be at war with Wahhabism. Since the Saudis are unlikely to change their state religion (could the US abandon its religious right?), this means war with Saudi Arabia. The only way the US and world economy could survive such a war is for Iraq to export a lot of oil.

It will be one of the great ironies of history if Iraq of 2006, with US support, joins Kuwait in seizing the Saudi oil fields that Saddam sought in the first Gulf War.

Of course we COULD take measures to increase our energy efficiency and increase our room to maneuver. Not under this president, alas.

Thursday, November 27, 2003

Is Saddam smarter than Bush/Rumsfeld?

Tom Friedman: Letter From Tikrit
Friedman makes a good case that Saddam planned the war better than Bush/Rumsfeld. I remember confident predictions by Bush administration figures and journalists that Saddam wasn't the kind of guy to survive in basements as a hunted fugitive. Wrong.

Bush, based on his college results, is probably about average Yale intelligence, meaning he's quite smart. Rumsfeld is reputed to be very clever, but he is apparently delusional. Saddam, based on the evidence, may be much smarter than both of them, and far less delusional. The US has to stop imagining it's dealing with an incompetent penny ante dictator, and start thinking of Saddam as a particularly cunning variant of Josef Stalin.

Wednesday, November 26, 2003

Clintonian healthcare reform: two insider perspectives

Notes: Robert Rubin's View of Health Care Reform: Archive Entry From Brad DeLong's Webjournal
The Clinton health care debacle was one of the great policy failures of the past 40 years. It was such a disaster that it set health care policy in the US back at least 10 years, and probably 15 years. DeLong was an insider, Rubin had a different angle. Their stories are interesting.

Tuesday, November 25, 2003

The Bush War on Terror: Time to try something different?

The Scorecard
More than two years after the World Trade Center towers came down and the President declared his 'war on terrorism,' it seems reasonable to offer a little scorecard on the 'war(s)' of choice for this administration.

Well worth reading, this editorial/blog doesn't say anything new, but it's a good summary with some very good links. On the plus side al Qaeda and its ilk seem to be focusing on limited attacks, but the minuses are very big. Fundamentally the Bush administration has failed in their approach.

One novel observation I hadn't thought of. Bush can't quit Iraq while Sadaam is free, it's too politically risky.

Saturday, November 22, 2003

London chemical plot foiled ... how smart is al Qaeda these days?

FT.com / World
The would-be terrorists made mistakes: the quantities they sought were so enormous - and the reasons they gave for buying them so unbelievable - that suspicions were immediately aroused. In addition some experts doubt that their plot could have worked.

Prior to 9/11 al Qaeda seems to have had some very bright and evil people. Some died in that attack, others died in Afghanistan or by assassination or have been captured. Zawahiri may be the smartest of the group left at large, but he seems to spend most of his energy hiding.

This story suggests that the bench may be thin, something I've wondered ever since the spectacularly incompetent "shoe bomber" effort. Al Qaeda has no problem attracting canon fodder, but it may be failing to recruit and retrain the most dangerous operatives: educated, intelligent, creative, cruel and viscious fundamentalists. One in a thousand adults may combine creativity and intelligence, but these may be inversely correlated with fundamentalism and cruelty. A relatively small talent pool limits Al Qaeda's capabilities.

This also suggests a reasonable strategy. The US employed Russian physicists after the collapse of the USSR, in part to keep them out of dangerous pursuits. Interventions which divert talented individuals from al Qaeda towards more wholesome pursuits will not make al Qaeda and its children vanish, but it will make them far less dangerous.

Friday, November 21, 2003

Shades of Vietnam: deserting to Canada

Some soldiers would rather desert than return to Iraq : Vancouver Indymedia
CBS did a piece on this recently, so it's getting some mainstream media coverage. A friend who lives in the American south, where most of our soldiers come from, tells me that the local news outlets are reporting on desretions. Hard to tell how big this is. The stress on guardsmen in particular is terrible.

Thursday, November 20, 2003

The Arar Case: Ashcroft sends a Canadian for torture in Syria

At the Bottom of the Slippery Slope: Archive Entry From Brad DeLong's Webjournal
Arar somehow got on a potentially-linked-to-terrorism watch list, was stopped on his way through the US and questioned for two weeks, and was then deported into Syrian custody despite being a Canadian citizen and resident. He was born in Syria and holds Syrian citizenship as well, and this was the 'pretext' for deporting him to Syria rather than Canada for questioning. As far as I know nobody in the US administration has denied that the intent of deporting him to Syria was that he be questioned by the Syrians - they sure weren't just deciding he shouldn't be in the US and deporting him (he's a Canadian resident, and was traveling on a connection through the US rather than entering it).

During a previous national psychotic episode, we interned a large number of Americans who had ancestors born in Japan.

Did we torture any of them?

If the torture angle is a modern innovation, one could make a case that we've outdone ourselves.

Of course Ashcroft should be removed. It's easy to understand why so much of Europe considers the US to be a sort of proto-Nazi state. There are days when I worry as well.

Sunday, November 16, 2003

NYT: Middle Class Losing Health Insurance

For Middle Class, Health Insurance Becomes a Luxury
... Mr. Thornton is one of more than 43 million people in the United States who lack health insurance, and their numbers are rapidly increasing because of ever soaring cost and job losses. Many states, including Texas, are also cutting back on subsidies for health care, further increasing the number of people with no coverage.

The majority of the uninsured are neither poor by official standards nor unemployed. They are accountants like Mr. Thornton, employees of small businesses, civil servants, single working mothers and those working part time or on contract.

It's like watching a slow motion train wreck; as inevitable as gravity. This may turn out to be the stealth issue of the 2004 elections; by then the effects will be noticeable.

Humans have a degree of empathy, but it's fairly limited. Our empathic tendencies evolved so that they are triggered by proximal input -- things we see and feel. We have more empathy for a wounded squirrel than for millions of Americans lacking access to reasonable health care (forget the rest of humanity, such as the Iraqi bystanders who are routinely omitted from fatality counts). It's not logical or admirable, it's just the way we are. So most Americans have ignored the healthcare crisis. They can't do that any more. Even if they don't feel it themselves, their friends, neighbors, and family will experience it. So now the real discussion begins.

We even know how it will turn out. We've known for at least 10 years, probably 20 years or more. A lot of money will drain out of healthcare. Pharmaceutical share prices, physician subspecialist salaries, etc. will fall dramatically. That's a side-effect though, it won't make the problem go away. We'll see some from of mandated risk pooling (single payor systems are just an extreme version of mandated risk sharing or pooling) and we'll see explicit rationing. The form those will take is less predictable (single payor, managed care, whatever); but only the surface forms can vary. The underlying principles -- risk sharing and rationing, are unavoidable.

Rationing doesn't require legislation. Risk sharing requires BIG time legislation. It's the risk sharing part that will be the issue in the 2004 elections.

I personally like some of the more modern variations on "medical savings accounts" aka "defined contributions" aka "patient-focused benefits" etc. etc. They're all aligning some aspects of cost, decision making and resource consumption, undoing the huge flaw in traditional insurance systems. These are details though, the real issues are rationing and risk sharing.

Friday, November 14, 2003

USATODAY.com - Scientists create a virus that reproduces

USATODAY.com - Scientists create a virus that reproduces
... genomics pioneer Craig Venter announced that his research group created an artificial virus based on a real one in just two weeks' time. When researchers created a synthetic genome (genetic map) of the virus and implanted it into a cell, the virus became "biologically active," meaning it went to work reproducing itself. Venter cautioned that the creation of artificial human or animal life is a long way off because the synthetic bacteriophage — the virus that was created — is a much simpler life form.

Two weeks to a created life form. Another day, another epic milestone in biotechnology. Once this would have been front page news.

I doubt this will be properly discussed. Sometimes I see our future as an oncoming train, and all of humanity is a deer on the tracks, frozen by the headlight.

SARS: What happened, anyway?

SARS: Epidemiology, Clinical Presentation, Management, and Infection Control Measures. Priya Sampathkumar, Zelalem Temesgen, Thomas F. Smith, and Rodney L. Thompson. Mayo Clinic Proceedings, July 2003
A reasonable overview, and rather nicely available on the public web. It didn't answer my questions though. The entire SARS story puzzles the heck out of me. Why did so many nurses die, even in locations that should have had strong infection control? Why did the disease seem so contagious in some places, and not at all contagious in others? Did the virus attenuate? Was the epidemiologic behavior due to an unidentified cofactor infection that was common in some places and not in others? (eg. a second virus was needed to develop full fledged SARS).

I can't believe that the infection control measures were so effective. The disease was loose in China for months. Why did it not spread in India at all?

The neurobheavioral effects of beta blockers and other medications

Economist.com | Memory and emotion
Previous work had established that emotion-associated enhancement of memory is caused, at least in part, by the action of stress hormones, in particular norepinephrine, on a part of the brain called the amygdala. He wondered if a similar mechanism was at work in the emotion-associated memory loss the team discovered.

The action of norepinephrine on the amygdala can be blocked by a drug called propranolol. When the researchers repeated their experiments on volunteers who had been dosed with this drug, they found, as expected, that those volunteers did not remember emotional words any better than neutral ones. In addition, however, they found that memory for neutral words which preceded emotional ones improved.

This comment, a small aside in an article on memory and emotion, woke me up. Beta blockers (propranolol, atenolol, etc) are very widely used medications. I'd never heard that they blocked norepinephrine action on the amygdala. I'd expect that to have an intriguing range of longterm neuropsychiatric actions. I'd love to see the full list.

On the other hand propranolol is an older beta blocker. The more common modern versions do not cross the blood-brain barrier as readily and might not have the same effects.

This is a good reminder, however, that the body uses the same substances and receptors to do very different things. The interpretations of the same substance/receptor combination depend on location (gut, brain, heart, etc). Actions on the brain may be the most subtle least appreciated of these. ACE inhibitors, for example, seem to have antidepressant or pro-euphoric activity, as well as inducing coughing in many people. I've long wondered what the longterm neurobehavioral effects of oral contraceptives have been...

Tuesday, November 11, 2003

War: It's not inevitable (NYT)

Is War Our Biological Destiny?
Admittedly, war making will be a hard habit to shake. "There have been very few times in the history of civilization when there hasn't been a war going on somewhere," said Victor Davis Hanson, a military historian and classicist at California State University in Fresno. He cites a brief period between A.D. 100 and A.D. 200 as perhaps the only time of world peace, the result of the Roman Empire's having everyone, fleetingly, in its thrall.

Archaeologists and anthropologists have found evidence of militarism in perhaps 95 percent of the cultures they have examined or unearthed. Time and again groups initially lauded as gentle and peace-loving — the Mayas, the !Kung of the Kalahari, Margaret Mead's Samoans, — eventually were outed as being no less bestial than the rest of us. A few isolated cultures have managed to avoid war for long stretches. The ancient Minoans, for example, who populated Crete and the surrounding Aegean Islands, went 1,500 years battle-free; it didn't hurt that they had a strong navy to deter would-be conquerors.

This article by Natalie Angier is one of the most uplifting I've read in some time. Viewed across the span of our brief history, it seems one can make a convincing case that we're getting more civilized with time. (Considering that some believe our ancestors were a band of rapacious psychotics who ate their cousins, we're arguably MUCH nicer than we were 150,000 years ago.) The race between our civilizing tendencies and the power of our weaponry might be a good focus for large bets -- by anyone not residing on earth!