Gender imbalance in China: the contribution of Hepatitis B infection

The Search for 100 Million Missing Women - An economics detective story. By Stephen J. Dubner and Steven D. Levitt

Fascinating. There are two fascinating claims here that seem reasonably persuasive:

1. Hepatitis B infection biases live births to male infants. (Hep B infection is very common in some areas of China and used to be very common in Taiwan -- until they began immunizing newborns to prevent perinatal infection.)
2. This phenomena accounts for a significant portion of China's gender bias (too few women -- the other explanations are selective neglect of liveborn girls and selective abortion, the old explanation of 'stopping after the first boy' doesn't work).

Economics and public health are meeting in increasingly interesting ways.

Signs of the end times? Or just new times ...

First - Crooked Timber: I think I’m going to be sick: The Economist’s new venture is:

...an inspirational lifestyle magazine which instead of helping readers make decisions in their professional life, helps them do the same in their personal life”...

... Take white-collar boxing – the latest stress reliever for Wall Street and City elite. Tired of punching a bag at the gym, they have now moved on to punching each other in front of a paying audience. ...

... If smacking around your colleagues doesn’t sound appealing, how about brushing up on your space travel tips so you can be first in line to book your space flight?

... Other articles include the latest on gadgets, health innovations, luxury items and how to order your own bespoke car.

and ...

The April 22, 2005 business section of a "local" paper, the St. Paul Pioneer Press, printed the compensation rankings for the CEOs of publicly traded Minnesota companies (the numbers are in millions of dollars, they don't distinguish between CEO-founders and CEO's hired into a mature company):

1. William McGuire, UnitedHealth Group: 125
2. Robert Ulrich, Target: 40
3. Jerry Grundhofer, US Bancorp: 39
4. Steve Sanger, General Mills: 18
5. Randall Hogan, Pentair: 10
6. Joel Ronning, Digital River: 8.6
7. James McNerney, 3M: 8.5
8. Kendrick Melrose, Toro: 8.1
9. Richard Rompala, Valspar: 7.8
10. Arthur Collins, Medtronic: 6.7

and

• the Wall Street Journal has a front page essay on America's rigid class structures
• the New York Times runs an entire series on the same topic
• Cohen and DeLong write in The Atlantic about globalization and class upheaval in near-future America. The primary thesis? There will be vastly more money and wealth going to multinational companies, but it will not go to workers exposed to the income pressures of globalization. Where it will end up settling (deflation, shareholders, senior management) is unclear and may depend on social factors such as corruption.
  

There's more, but the above provides a decent overview. We are an aging society, so we may respond to these circumstances with less social upheaval than we would have 80 years ago. All the same, I do expect a green/socialist party to emerge in America in 2012, rather to the shock of pundits everywhere. (I'm a middle-of-the-road Clinton Democrat myself btw, but I'm old too :-).

Search engines I use now

At the pretty wired (ok, it was in Minnesota) .com startup I worked for in the 90s I was the first to discover and use Google. Alta Vista, my old favorite, had been in decline and Yahoo was still pretty much a directory/indexing company (for manual indices, I then preferred the Encyclopedia Britannica's site!).

Google was the clear winner from the start. It's been a Google world ever since.

There are rumblings, though, of rebellion. Googe's indexing engines are slow to hit many pages, especially Gooogle's own blogs. Yahoo seems to hit the pages Google misses. And, as Phil Bradley notes, there are many special purpose alternatives.

Here are a few I've lately found useful - or at least interesting:

Mindset (Yahoo): Yahoo search biased to commercial or non-commercial
http://mindset.research.yahoo.com

Grokker: visual results
http://www.grokker.com

Brainboost: just facts
http://www.brainbost.com

Google Scholar: academia
http://scholar.google.com

Google Portal: Google + Gmail + Google History search
http://www.google.com/ig

Froogle and Pricescan: Shopping, also Amazon for the best overall user reviews.

Google Print: search full text of books
(added 5/28, thanks to a reference from Phil Bradley's blog)
http://print.google.com/

Water boarding and other American recreational activities

The Torture Feature: Taxonomy of Torture

Form Direct Questioning to Sleep deprivation to Isolation to Water boarding to old-fashined beatings-to-death. All unremarkable everyday routines in modern America and our outsourced torture sites.

Intelligent design: the game of Spore

BBC NEWS | Technology | Sims creator takes on evolution

In the game, players start off as an amoeba in a 2D world, reminiscent of some early video games.

The aim is to grow and evolve generations of creatures, with players able to choose the physical attributes of their creation.

"You get to play every generation of the creature," said Mr Wright. "I want something boys can make scary things or casual gamers can make cute things."

He said the computer would analyse a creature's design and work out how it should behave.

In the demonstration, Mr Wright created a three-legged creature and said the software would work out how it should walk.

"This is the hardest piece of technology I have ever had to solve," he said.

The creatures are supposed to evolve through natural selection, and intelligent design. As I've noted in the context of another game, SkyNet comes not from the integrated missile defense system, but rather from the first generation of networked games that includes rat neural tissue in the networked game consoles ...

Security costs money, it's cheaper for banks to pay the crooks.

PBS | I, Cringely . May 26, 2005 - Phish or Phisher?

Cringely tackles phishing scams, and he's sufficiently impolitic to point out why credit card companies and banks don't fuss about this fraud:

Another problem is that a large group of phishing victims -- banks and credit card companies -- don't want to publicize their losses, which might lead to a loss of business as customers start to worry about being victimized. But it goes even further, because the financial institutions are only on the hook for reported thefts. So by not making a big deal of it, maybe you won't notice that extra $30 charge and won't demand that your credit card company cover the loss. Being upfront about phishing could easily double corporate losses because of it by forcing these outfits to actually assume the risk that they say they'll assume.

So nobody talks about it, and the costs of phishing are generally hidden in the average eight percent that credit card companies figure they'll lose through theft, bankruptcies, etc. In a business with interest charges often going above 20 percent, phishing is tolerable...

This has been true forever. When credit cards started being used outside of brick-and-mortar settings fraud and identity theft exploded -- but the costs of fraud are still much less than the costs of preventing fraud. Especially if the victims don't notice their losses.

It's no different with checks. Check fraud is a very common crime, but in general the banks and police don't bother to bring these cases to court. It's just not worth the hassle -- for them.

Of course we bear the costs, but that's another story. Happily there are plausible solutions:

... Thinking there must be a better solution I contacted Max Levchin, who used to chase phishers for a living as co-founder and CTO of PayPal, a company he left a few months after it was bought by eBay back in 2002.

"The way to nail phishing," says Max, "is for the companies being impersonated to offer cash bounties -- to the first person to report the incident, the first person to call the free host and take down the site, the first person who figures out the identity of the perp. This would mean admitting that the matter is much more serious than most people realize, but that's going to have to happen, sooner than later, if columns like yours continue to give coverage to the matter. On the other hand, it's peanuts, financially, for the companies involved. There is the adverse selection problem -- why not set up phishing sites, report them, and collect the bounties? -- but it's easy to mitigate this by making the pay-outs contingent on all kinds of personal information from the good samaritan, and making the bounties really significant financially only when criminal charges are brought against the perpetrators. In fact, about a year ago, I was thinking of starting a site that would be an independent agency, holding the bounty money in escrow, ensuring the actual payments, and providing the war-room-style up-to-the-second information about what the latest phishing scams were. In the end, I decided this was a project not too different from my PayPal work, and I could do more fun things with my personal time, but still think the idea is sound."

Race as a collection of genes that travel together

The New York Times > Opinion > Op-Ed Contributor: A Family Tree in Every Gene

The thesis of the article is that genes tend to travel together and that it's possible to assign a human being to a geographically isolated population in which that the gene set was very common. That assignment group can be called a "race" (actually, from the article, it might even be a "tribe" or "extended family") and this theory is a statistical (rather than cultural) model of "race".

This makes sense to me. I've been skeptical of passionate statements that "race does not exist" -- they reminded me of the earnest statements that "intelligence is not genetically determined". Well intentioned, but unpersuasive.

The New York Times
March 14, 2005
A Family Tree in Every Gene
By ARMAND MARIE LEROI

Armand Marie Leroi, an evolutionary developmental biologist at Imperial College in London, is the author of "Mutants: On Genetic Variety and the Human Body."

... The dominance of the social construct theory [jf: of race, vs. the genetic theory] can be traced to a 1972 article by Dr. Richard Lewontin, a Harvard geneticist, who wrote that most human genetic variation can be found within any given "race." If one looked at genes rather than faces, he claimed, the difference between an African and a European would be scarcely greater than the difference between any two Europeans. A few years later he wrote that the continued popularity of race as an idea was an "indication of the power of socioeconomically based ideology over the supposed objectivity of knowledge." Most scientists are thoughtful, liberal-minded and socially aware people. It was just what they wanted to hear.

Three decades later, it seems that Dr. Lewontin's facts were correct, and have been abundantly confirmed by ever better techniques of detecting genetic variety. His reasoning, however, was wrong. His error was an elementary one, but such was the appeal of his argument that it was only a couple of years ago that a Cambridge University statistician, A. W. F. Edwards, put his finger on it.

The error is easily illustrated. If one were asked to judge the ancestry of 100 New Yorkers, one could look at the color of their skin. That would do much to single out the Europeans, but little to distinguish the Senegalese from the Solomon Islanders. The same is true for any other feature of our bodies. The shapes of our eyes, noses and skulls; the color of our eyes and our hair; the heaviness, height and hairiness of our bodies are all, individually, poor guides to ancestry.

But this is not true when the features are taken together. Certain skin colors tend to go with certain kinds of eyes, noses, skulls and bodies. When we glance at a stranger's face we use those associations to infer what continent, or even what country, he or his ancestors came from - and we usually get it right. To put it more abstractly, human physical variation is correlated; and correlations contain information.

Genetic variants that aren't written on our faces, but that can be detected only in the genome, show similar correlations. It is these correlations that Dr. Lewontin seems to have ignored. In essence, he looked at one gene at a time and failed to see races. But if many - a few hundred - variable genes are considered simultaneously, then it is very easy to do so. Indeed, a 2002 study by scientists at the University of Southern California and Stanford showed that if a sample of people from around the world are sorted by computer into five groups on the basis of genetic similarity, the groups that emerge are native to Europe, East Asia, Africa, America and Australasia - more or less the major races of traditional anthropology...

...Yet there is nothing very fundamental about the concept of the major continental races; they're just the easiest way to divide things up. Study enough genes in enough people and one could sort the world's population into 10, 100, perhaps 1,000 groups, each located somewhere on the map. This has not yet been done with any precision, but it will be. Soon it may be possible to identify your ancestors not merely as African or European, but Ibo or Yoruba, perhaps even Celt or Castilian, or all of the above.

... The billion or so of the world's people of largely European descent have a set of genetic variants in common that are collectively rare in everyone else; they are a race. At a smaller scale, three million Basques do as well; so they are a race as well. Race is merely a shorthand that enables us to speak sensibly, though with no great precision, about genetic rather than cultural or political differences...

A statistical model of "race" implies a (pardon the language) sort of n-dimensional "bell curve". Imagine a 'gene-space' consisting of (say) 100 or so marker gene values. If we treat this a 100-dimension space then an individual human should appear as a point in this space. If we add a dimension for frequency then we may "see" (humans aren't good at visualizing 100 dimensions -- pending our upgrades) "mountains" in the space. Those are "races". Most of us are somewhere on the flank of a mountain, but there ought to be (how can one resist the word) "pure" folk at the peaks.

Yahoo Search drops the big one: non-commercial search

Yahoo! Mindset

Ooookkkaaaay. This is actually interesting. Yahoo's new "Mindset" search allows you to weight search results based on how "commercial" they are. I tested this by searching on product with the slider set to "non-commercial". Instead of Google's 50 pages of ads I got a very useful review in the 3rd hit.

Of all the search experiments I've seen in the past year this one has impressed me the most. In the search wars, filtering out 'commercial' sites is a dramatic and risky move.

Stanford Center for Clinical Informatics: Seminar series

2004-05 Seminars - Stanford Center for Clinical Informatics (SCCI) - Stanford University School of Medicine

This is a remarkable resource for medical computing/health informatics folks. Admittedly it's a small audience, but the collection of resources and speakers is remarkable. Kudos to Stanford for putting it online.

Our first interstellar probe - leaving the solar system

NASA - Voyager Enters Solar System's Final Frontier

Heading for the stars.

The consensus of the team now is that Voyager 1, at 8.7 billion miles from the Sun, has at last entered the heliosheath, the region beyond the termination shock," said Dr. John Richardson from MIT, Principal Investigator of the Voyager plasma science investigation.

Why did Palm Fail? A Slashdot thread.

PalmOne to become Palm Again; PalmSource & Linux

I wrote this comment in a very interesting Slashdot discussion. Lately Slashdot discussions have been quite boring; but this one has good comments (other than mine of course!). This comment from a Palm developer is particularly interesting.

When I teach about data interfaces in healthcare systems, and the complexity of integration, I compare Palm original representation of a 'contact' (address book entry) with Outlook/Exchange server's contact representation. The complexity (non-computable complexity in some areas) of synchronizing between these two was a huge problem for Palm. I'm not sure when they figured out how much trouble they were in, but once Microsoft took over the enterprise with Exchange server Palm's fate was pretty much sealed.

In later versions of the OS they tried to better match Outlook's data models, but they botched the software layer that provided some backwards compatibility (arguably they should have given up on the backwards compatibility, they ended up with the worst of two options).

Linux on the Palm is not as important, really, as matching the Exchange server data model.

More broadly, synchronization is a problem that's been grossly underestimated in many quarters. It often requires a fuzzy non-deterministic reconciliation of semantic models; the same challenge that Berners-Lee addresses in the context of the semantic web. This issue is a major part (along with some perverse economics) of why healthcare IT projects are so difficult.

I hope Palm now understands these issues, I fear that much of their intellectual capital may have moved on...

The immense power of denial: one handed professional ball players

...But I Went Out and Achieved Anyway! | MetaFilter

One hand. No arm. No leg. Lots of denial. Never underestimate the power of denial.

Action Squad: Minneapolis Urban Adventurers

Action Squad: Minneapolis Urban Adventurers

This was featured on metafilter, but they didn't mention this is a Minneapolis street gang! I may have met some of these guys. Reminds me of exploring steam tunnels at college -- but in those days Caltech allowed undergrads to have keys to many buildings, so it wasn't even trespassing (though it wasn't approved either).

My personal experience with urban adventures was limited to rooftop camping in the ancient days when I had far more time than money.

The treadmill desk -- coming soon to an office near you

New Weight-Loss Focus: The Lean and the Restless - New York Times

A researcher studying idiosyncratic non-exercise activity and weight loss installs a treadmill desk:

... At meetings, he stands instead of sitting. Talking on the telephone, he paces around. In his office he has a treadmill in place of a desk. He got it last year when he saw the data from the study comparing lean people and obese ones.

'My computer is stationed over the treadmill,' he said. 'I work at 0.7 miles an hour.'

A stand-up desk might seem simpler, but he prefers the treadmill.

'Standing still is quite difficult,' he said. 'You have a natural tendency to want to move your legs. Zero point seven is the key. You don't get sweaty, you can't jiggle too much. It's about one step a second. It's very comfortable. Most people seem to like it around 0.7.'

I've seen a few people in our office sitting on a large ball while working -- keeping stable would certainly burn calories. This takes things to the next step. I'd read that he'd done this, but I hadn't seen the speed setting -- 1 step a second seems quite pleasant.

All of can practice standing at meetings. Lose weight and get the meeting done faster ..

I wonder how long it will take to turn the "treadmill desk" into a commercial product. When that happens perhaps employers would consider paying for them through employee FlexPlan coverage.

The UK approach to patient privacy with electronic health records

Britain toughens patient privacy

We're unlikely to get such strong protections; historically US law does very little to protect privacy. It's nice to know someone's doing it however. In practice using the full power of these restrictions would be unwise for almost any patient, but it's easier to loosen such rules than to tighten them later. Emphases mine.

The United Kingdom's Health Department published tough new rules to guarantee that patients in England can control access to their electronic health care records in a system under development by the National Health Service.

The NHS National Programme for Information Technology kicked off a 10-year, $10 billion project in late 2003 to develop a nationwide e-health record (EHR) system for 50 million patients and 30,000 doctors in England. It would not cover Scotland, Wales or Northern Ireland.

The NHS Care Record Guarantee, published May 23, will allow patients to prevent information in their records from being shared, Health Ministry officials said. But the quality of care could deteriorate if patients block information sharing.

The health record guarantee also states that:

* Patients will be able to obtain a list of everyone who looks at their records.

* NHS will not share information outside the agency, particularly with other government agencies.

* Records will only be shared with health care providers or social service or education organizations with patient permission.

* NHS will take disciplinary action against anyone who accesses health records without permission or a good reason.

The new NHS electronic Care Records Service “has enormous potential benefits for patients," said Lord Warner, UK health minister. The system allows medical staff throughout England to have instant access to patient histories, including allergies, current medications and recent treatment.

Warner said the department developed the new privacy rules to address any patients’ concerns about the confidentiality of their records.

The Care Guarantee clearly establishes the rights of patients to control who has access to their information, Warner said. "These rules will be backed up with tough security measures to prevent unauthorized access to records, ensuring everyone can have confidence in the new system," he said.