Tuesday, March 17, 2020

Hydroxychloroquine, COVID-19, and Lupus

Researchers are taking seriously the use of hydroxychloroquine for COVID-19 therapy:
Both chloroquine and hydroxychloroquine inhibit SARS-CoV-2 in vitro, although hydroxychloroquine appears to have more potent antiviral activity [75].
I think saw a post somewhere that claimed it interferes with viral replication inside infected lung tissue but I can't find it now.

That's obviously great if it works out.

If it does work out though, it might be worth looking again at old (and still current) ideas that rheumatic disorders that response to hydroxychloroquine (esp. SLE, RA) are infectious in origin. Maybe an RNA virus ...

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